Human EDAR Recombinant Protein – Cat# MBS147299

Ectodysplasin A Receptor (EDAR) Human Recombinant Protein

Name: EDAR Recombinant Protein; Ectodysplasin A Receptor; Human; MyBioSource
Brand: MyBioSource
SKU: MBS147299
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS147299

Description: EDAR produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 413 amino acids (27-187a.a.) and having a molecular mass of 45.6kDa. (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). EDAR is… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ectodysplasin A Receptor (EDAR), Recombinant Protein

Full Product Name

Recombinant Human Ectodysplasin A Receptor, Sf9

Product Gene Name

EDAR recombinant protein

Product Synonym Names

Ectodysplasin A Receptor; Ectodysplasin 1; Anhidrotic Receptor; Anhidrotic Ectodysplasin Receptor 1; Ectodermal Dysplasia Receptor; Downless Homolog; EDA-A1 Receptor; DL; Tumor Necrosis Factor Receptor Superfamily Member EDAR; Downless; Mouse; Homolog Of; Ectodysplasin-A Receptor; ECTD10A; ECTD10B; EDA-A1R; EDA1R; ED1R; EDA3; HRM1; ED5; ED3; EDAR Human, Sf9; Ectodysplasin A Receptor Human Recombinant, Sf9

Sequence

ADP EYSNCGE NEYYNQTTGL CQECPPCGPG EEPYLSCGYG TKDEDYGCVP CPAEKFSKGG YQICRRHKDC EGFFRATVLT PGDMENDAEC GPCLPGYYML ENRPRNIYGM VCYSCLLAPP NTKECVGATS GASANFPGTS GSSTLSPFQH AHKELSGQGH LATAAAAFES ACSLEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSRDELTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGKHHH HHH.

Host

Sf9, Baculovirus cells

Form/Format

Sterile filtered colorless solution
Protein solution (0.5mg/ml) contains 10% glycerol & Phosphate Buffered Saline (pH 7.4)

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles

Molecular Weight

51,690 Da

OMIM

AF130988 mRNA

3D Structure

ModBase 3D Structure for Q9UNE0

Product Categories/Family for EDAR recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Ectodysplasin; EDAR Human; Sf9

Other Notes

Small volumes of EDAR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EDAR purchase

MBS147299 is a recombinant protein targeting EDAR. Also known as Recombinant Human Ectodysplasin A Receptor, Sf9. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for EDAR. It may not necessarily be applicable to this product.

NCBI GI #

21263572

NCBI GeneID

10913

NCBI Accession #

Q9UNE0.1

UniProt Primary Accession #

Q9UNE0

UniProt Secondary Accession #

Q52LL5; Q9UND9; B2R9H2; B4DLC5; D3DX74; E9PC98

UniProt Related Accession #

Q9UNE0

NCBI Official Full Name

Tumor necrosis factor receptor superfamily member EDAR

NCBI Official Synonym Full Names

ectodysplasin A receptor

NCBI Official Symbol

EDAR

NCBI Official Synonym Symbols

DL; ED3; ED5; ED1R; EDA3; HRM1; EDA1R; ECTD10A; ECTD10B; EDA-A1R

UniProt Protein Name

Tumor necrosis factor receptor superfamily member EDAR

UniProt Synonym Protein Names

Anhidrotic ectodysplasin receptor 1; Downless homolog; EDA-A1 receptor; Ectodermal dysplasia receptor; Ectodysplasin-A receptor

Protein Family

Tumor necrosis factor receptor superfamily

UniProt Gene Name

EDAR

UniProt Synonym Gene Names

NCBI Protein Information

tumor necrosis factor receptor superfamily member EDAR

NCBI Summary for EDAR

This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]

UniProt Comments for EDAR

Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death.

Research Articles on EDAR

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EDAR recombinant protein

Reference Product	PubMed Publications
EDA recombinant protein	>121 publications with EDAR and EDA
EDARADD recombinant protein	>51 publications with EDAR and EDARADD
TRAF2 recombinant protein	>5 publications with EDAR and TRAF2
SLC45A2 recombinant protein	>2 publications with EDAR and SLC45A2
SLC24A5 recombinant protein	>2 publications with EDAR and SLC24A5
CYLD recombinant protein	>1 publications with EDAR and CYLD
CTGF recombinant protein	>1 publications with EDAR and CTGF
TRAF3 recombinant protein	>1 publications with EDAR and TRAF3

Pathways associated with EDAR recombinant protein

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Integrated Breast Cancer Pathway antibodies	Integrated Breast Cancer Pathway Diagram

Diseases associated with EDAR recombinant protein

Disease Name	Pubmed Publications
Skin Diseases Antibodies	>72 publications with EDAR and Skin Diseases
Necrosis Antibodies	>71 publications with EDAR and Necrosis
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive Antibodies	>32 publications with EDAR and Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive
Nervous System Diseases Antibodies	>6 publications with EDAR and Nervous System Diseases
Inflammation Antibodies	>4 publications with EDAR and Inflammation
Fetal Death Antibodies	>2 publications with EDAR and Fetal Death
Eye Diseases Antibodies	>2 publications with EDAR and Eye Diseases
Immune System Diseases Antibodies	>2 publications with EDAR and Immune System Diseases
Chromosome Aberrations Antibodies	>2 publications with EDAR and Chromosome Aberrations
Hyperplasia Antibodies	>1 publications with EDAR and Hyperplasia

Organs/Tissues associated with EDAR recombinant protein

Organ/Tissue Name	Pubmed Publications
Mouth Antibodies	>35 publications with EDAR and Mouth
Embryonic Tissue Antibodies	>34 publications with EDAR and Embryonic Tissue
Brain Antibodies	>6 publications with EDAR and Brain
Heart Antibodies	>3 publications with EDAR and Heart
Kidney Antibodies	>1 publications with EDAR and Kidney
Uncharacterized Tissue Antibodies	>1 publications with EDAR and Uncharacterized Tissue
Prostate Antibodies	>1 publications with EDAR and Prostate