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F2RL2 Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS001473

MBS001473 is an antibody targeting F2RL2. Also known as Rabbit F2RL2 Antibody. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
F2RL2, Antibody
Full Product Name
Rabbit F2RL2 Antibody
Product Gene Name
Host
Rabbit
Species Reactivity
Human
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Molecular Weight
42,508 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (75911307..75919259, complement). Location: 5q13
OMIM
601919
3D Structure
ModBase 3D Structure for O00254
Applications Tested/Suitable for anti-F2RL2 antibody
Immunofluorescence (IF), ELISA (EIA)

Other Notes

Small volumes of anti-F2RL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for F2RL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
proteinase-activated receptor 3 isoform 2
NCBI Official Synonym Full Names
coagulation factor II (thrombin) receptor-like 2
NCBI Official Symbol
F2RL2
NCBI Official Synonym Symbols
PAR3; PAR-3
UniProt Protein Name
Proteinase-activated receptor 3
UniProt Synonym Protein Names
Coagulation factor II receptor-like 2; Thrombin receptor-like 2
UniProt Gene Name
F2RL2
UniProt Synonym Gene Names
PAR3; PAR-3
UniProt Entry Name
PAR3_HUMAN
NCBI Protein Information
proteinase-activated receptor 3; thrombin receptor-like 2; protease-activated receptor 3; proteinase-activated receptor-3; Coagulation factor II receptor-like 2 (protease-actovated receptor 3)

NCBI Summary for F2RL2

This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]
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UniProt Comments for F2RL2

PAR3: a G-protein coupled receptor for activated thrombin or trypsin. Coupled to G proteins that stimulate phosphoinositide hydrolysis. Interacts with INSC/inscuteable and probably GPSM2. Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 5q13

Cellular Component: integral to plasma membrane; apical plasma membrane; plasma membrane; extracellular region

Molecular Function: protein binding; phosphoinositide phospholipase C activity; thrombin receptor activity

Biological Process: platelet activation; metabolic process; response to wounding; blood coagulation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-F2RL2 antibody

 Reference Product  PubMed Publications
 F2RL3 antibody  >1 publications with F2RL2 and F2RL3

Diseases associated with anti-F2RL2 antibody

Organs/Tissues associated with anti-F2RL2 antibody

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