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Splicing Factor 45 (RBM17) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1474518

This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on… More details

$1140 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Splicing factor 45 (Rbm17), Recombinant Protein
Full Product Name
Recombinant Mouse Splicing factor 45 (Rbm17)
Product Gene Name
Rbm17 recombinant protein
Product Synonym Gene Name
Rbm17
Sequence
SLYDDLGVET SDSKTEGWSK NFKLLQSQLQ VKKAALTQAK SQRTKQSTVL APVIDLKRGG SSDDRQIADT PPHVAAGLKD PVPSGFSAGE VLIPLADEYD PMFPNDYEKV VKRQREERQR QRELERQKEI EEREKRRKDR HEASGFSRRP DPDSDEDEDY ERERRKRSMG GAAIAPPTSL VEKDKELPRD FPYEEDSRPR SQSSKAAIPP PVYEEPDRPR SPTGPSNSFL ANMGGTVAHK IMQKYGFREG QGLGKHEQGL STALSVEKTS KRGGKIIVGD ATEKGEAQDA SKKSDSNPLT EILKCPTKVV LLRNMVGAGE VDEDLEVETK EECEKYGKVG KCVIFEIPGA PDDEAVRIFL EFERVESAIK AVVDLNGRYF GGRVVKACFY NLDKFRVLDL AEQV
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
45,304 Da
Sequence Positions
2-405, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8JZX4
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Rbm17 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rbm17 purchase

MBS1474518 is a recombinant protein targeting Rbm17. Also known as Recombinant Mouse Splicing factor 45 (Rbm17). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Rbm17. It may not necessarily be applicable to this product.

NCBI GI #
22779924
NCBI GeneID
76938
NCBI Accession #
NP_690037.1
UniProt Primary Accession #
Q8JZX4
UniProt Secondary Accession #
O75939; A2AP41
UniProt Related Accession #
Q8JZX4
GenBank Nucleotide #
NM_152824.1
NCBI Official Full Name
splicing factor 45
NCBI Official Synonym Full Names
RNA binding motif protein 17
NCBI Official Symbol
Rbm17
NCBI Official Synonym Symbols
2700027J02Rik
UniProt Protein Name
Splicing factor 45
UniProt Synonym Protein Names
45 kDa-splicing factor; RNA-binding motif protein 17
Protein Family
Splicing factor
UniProt Gene Name
Rbm17
UniProt Synonym Gene Names
Spf45
NCBI Protein Information
splicing factor 45

UniProt Comments for Rbm17

Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites ().

Research Articles on Rbm17

1. we found a significant overlap in genes that undergo both RBM17- and TDP-43-dependent cryptic splicing repression, many of which are associated with survival. We propose that repression of cryptic splicing by RBPs is critical for neuronal health and survival

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Rbm17 recombinant protein

 Products by Pathway  Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram

Diseases associated with Rbm17 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with Rbm17 and Neoplasms
 Nervous System Diseases Antibodies  >3 publications with Rbm17 and Nervous System Diseases
 Spinocerebellar Ataxias Antibodies  >3 publications with Rbm17 and Spinocerebellar Ataxias
 Ovarian Neoplasms Antibodies  >2 publications with Rbm17 and Ovarian Neoplasms
 Carcinoma Antibodies  >2 publications with Rbm17 and Carcinoma
 Breast Neoplasms Antibodies  >1 publications with Rbm17 and Breast Neoplasms
 Lung Neoplasms Antibodies  >1 publications with Rbm17 and Lung Neoplasms
 Pancreatic Neoplasms Antibodies  >1 publications with Rbm17 and Pancreatic Neoplasms
 Drug Toxicity Antibodies  >1 publications with Rbm17 and Drug Toxicity
 Hematologic Diseases Antibodies  >1 publications with Rbm17 and Hematologic Diseases

Organs/Tissues associated with Rbm17 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with Rbm17 and Blood
 Prostate Antibodies  >2 publications with Rbm17 and Prostate
 Lung Antibodies  >1 publications with Rbm17 and Lung
 Bladder Antibodies  >1 publications with Rbm17 and Bladder
 Liver Antibodies  >1 publications with Rbm17 and Liver
 Brain Antibodies  >1 publications with Rbm17 and Brain
 Pancreas Antibodies  >1 publications with Rbm17 and Pancreas
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