• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MMACHC-Like Protein (cblc-1) Caenorhabditis Elegans Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1475913

MBS1475913 is a recombinant protein targeting cblc-1. Also known as Recombinant Caenorhabditis elegans MMACHC-like protein (cblc-1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$955 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MMACHC-like protein (cblc-1), Recombinant Protein
Full Product Name
Recombinant Caenorhabditis elegans MMACHC-like protein (cblc-1)
Product Gene Name
cblc-1 recombinant protein
Product Synonym Gene Name
cblc-1
Sequence
MVTEMSHAES IKRVVDQKLS SHEGFESHMF KIGSYNEAVG ESSPFALPYD DSTMALLILS TPDMFDVAFR KWVVQKTMDF GSFDEVCEMV SSPIQSFLED RLEIMSEKLR KVEENFEILH DYSMTPQRRP KILMQTCGHV AGAAFYYQPC HFQEDGVTWP PAGRMGPNLK FIGLSLHPIY GGHFAFRSVL IFPNVKIPEF CEKEPRPILT ASEDVRTALE KFNYNWKDSG FRDFGNPTRR YSTTQMEFFG RPVAERWEVL RPWVDGGAKN ID
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
31,291 Da
Sequence Positions
1-272, Full length
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q7Z144
Species
Caenorhabditis elegans
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of cblc-1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for cblc-1. It may not necessarily be applicable to this product.

NCBI GI #
71998896
NCBI GeneID
3565644
NCBI Accession #
NP_001022524.1
UniProt Primary Accession #
Q7Z144
UniProt Related Accession #
Q7Z144
GenBank Nucleotide #
NM_001027353.4
NCBI Official Full Name
MMACHC-like protein
NCBI Official Symbol
cblc-1
UniProt Protein Name
MMACHC-like protein
UniProt Synonym Protein Names
Cobalamin deficiency protein 1; Cyanocobalamin reductase (cyanide-eliminating)
Protein Family
MMACHC-like protein
UniProt Gene Name
cblc-1
NCBI Protein Information
MMACHC-like protein

UniProt Comments for cblc-1

Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate. Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione-dependent reductive demethylation of adenosylcobalamin. Under anaerobic conditions cob(I)alamin is the first product; it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen. Binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives.
Show more

Research Articles on cblc-1

1. The crystal structure of ceCblC provides insights into how architectural differences at the alpha- and beta-faces of cobalamin promote the thiol oxidase activity of ceCblC but mute it in wild-type human CblC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with cblc-1 recombinant protein

 Reference Product  PubMed Publications
 mmcm-1 recombinant protein  >2 publications with cblc-1 and mmcm-1
 mmaa-1 recombinant protein  >2 publications with cblc-1 and mmaa-1
 mmab-1 recombinant protein  >2 publications with cblc-1 and mmab-1
 mce-1 recombinant protein  >1 publications with cblc-1 and mce-1
 pcca-1 recombinant protein  >1 publications with cblc-1 and pcca-1
 pccb-1 recombinant protein  >1 publications with cblc-1 and pccb-1

Pathways associated with cblc-1 recombinant protein

 Products by Pathway  Pathway Diagram
 Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway antibodies  Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway Diagram
 Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies  Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram
 Defective BTD Causes Biotidinase Deficiency Pathway antibodies  Defective BTD Causes Biotidinase Deficiency Pathway Diagram
 Defective CD320 Causes Methylmalonic Aciduria Pathway antibodies  Defective CD320 Causes Methylmalonic Aciduria Pathway Diagram
 Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies  Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram
 Defective GIF Causes Intrinsic Factor Deficiency Pathway antibodies  Defective GIF Causes Intrinsic Factor Deficiency Pathway Diagram
 Defective HLCS Causes Multiple Carboxylase Deficiency Pathway antibodies  Defective HLCS Causes Multiple Carboxylase Deficiency Pathway Diagram
 Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway antibodies  Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway Diagram
 Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway antibodies  Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway Diagram
 Defective MMAB Causes Methylmalonic Aciduria Type CblB Pathway antibodies  Defective MMAB Causes Methylmalonic Aciduria Type CblB Pathway Diagram
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000