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Deleted in Bladder Cancer Protein 1 Homolog (DBC1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1476129

This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5 CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder… More details

$1605 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Deleted in bladder cancer protein 1 homolog (Dbc1), Recombinant Protein
Full Product Name
Recombinant Rat Deleted in bladder cancer protein 1 homolog (Dbc1)
Product Gene Name
Dbc1 recombinant protein
Product Synonym Gene Name
Dbc1
Sequence
RISVQPSHQE PAGTDQHVSK EFDWLISDRG PFHHSRSYLS FVERHRQGFT TRYKIYREFA RWKVRNTAIE RRDLVRHPVP LMPEFQRSIR LLGRRPTTQQ FIDTIIKKYG THLLISATLG GEEALTMYMD KSRLDRKSGN ATQSVEALHQ LASSYFVDRD GTMRRLHEIQ ISTGAIKVTE TRTGLLGCNS YDNLDSVSSV LLQSTESKLH LQGLQIIFPQ YLQEKFVQSA LSYIMCNGEG EYVCQNSQCR CQCAEEFPQC NCPITDIQIM EFTLANMAKA WTEAYKDLEN SDEFKSFMKR LPSNHFLTIG SIHQHWGNDW DLQSRYKLLQ SATEAQRQKI QRTARKLFGL SVRCRHNPNH QLPRERTIQQ WLARVQSLLY CNENGFWGTF LESQRSCVCH GSTTLCQRPI PCIIGGNNSC AMCSLANISL CGSCNKGYKL YRGRCEPQNV DSERSEQFIS FETDLDFQDL ELKYLLQKMD SRLYVHTTFI SNEIRLDTFF DLRWRKRMSL TLKSNKNRMD FIHMVIGMSM RICQMRNSSL DPMFFVYVNP FSGSHSEGWN MPFGEFGYPR WEKIRLQNSQ CYNWTLLLGN RWKTFFETVH IYLRSRTRLP TLRNETGQGP VDLSDPSKRQ FYIKISDVQV FGYSLRFNAD LLRSAVQQVN QSYTQGGQFY SSSSVMLLML DIRDRINRLA PPVAPGKPQL DLFSCMLKHR LKLTNSEIIR VNHALDLYNT EILKQSDQMT AKLC
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
88,654 Da
Sequence Positions
17-760, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q925T8
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Dbc1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dbc1 purchase

MBS1476129 is a recombinant protein targeting Dbc1. Also known as Recombinant Rat Deleted in bladder cancer protein 1 homolog (Dbc1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Dbc1. It may not necessarily be applicable to this product.

NCBI GI #
17978461
NCBI GeneID
140610
NCBI Accession #
NP_536730.1
UniProt Primary Accession #
Q925T8
UniProt Related Accession #
Q925T8
GenBank Nucleotide #
NM_080482.2
NCBI Official Full Name
BMP/retinoic acid-inducible neural-specific protein 1
NCBI Official Synonym Full Names
BMP/retinoic acid inducible neural specific 1
NCBI Official Symbol
Brinp1
NCBI Official Synonym Symbols
Dbc1; Dbccr1
UniProt Protein Name
BMP/retinoic acid-inducible neural-specific protein 1
UniProt Synonym Protein Names
Deleted in bladder cancer protein 1 homolog
UniProt Gene Name
Brinp1
UniProt Synonym Gene Names
Brinp; Dbc1; Dbccr1; Fam5a
NCBI Protein Information
BMP/retinoic acid-inducible neural-specific protein 1

NCBI Summary for Dbc1

human homolog involved in mediating cell death in cultured bladder tumor cells [RGD, Feb 2006]

UniProt Comments for Dbc1

Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway ().

Research Articles on Dbc1

1. The findings of this study identify a role for RLR signaling and type I IFN in regulating astrocyte innate immune responses after SCI. (c) 2011 Wiley Periodicals, Inc.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Dbc1 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >36 publications with Dbc1 and Neoplasms
 Urinary Bladder Neoplasms Antibodies  >15 publications with Dbc1 and Urinary Bladder Neoplasms
 Carcinoma Antibodies  >14 publications with Dbc1 and Carcinoma
 Breast Neoplasms Antibodies  >12 publications with Dbc1 and Breast Neoplasms
 Recurrence Antibodies  >6 publications with Dbc1 and Recurrence
 Leukemia Antibodies  >4 publications with Dbc1 and Leukemia
 Lung Neoplasms Antibodies  >4 publications with Dbc1 and Lung Neoplasms
 Carcinoma, Squamous Cell Antibodies  >3 publications with Dbc1 and Carcinoma, Squamous Cell
 Carcinoma, Papillary Antibodies  >3 publications with Dbc1 and Carcinoma, Papillary
 Neoplasms, Experimental Antibodies  >3 publications with Dbc1 and Neoplasms, Experimental

Organs/Tissues associated with Dbc1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >1 publications with Dbc1 and Eye
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