Human CHIC2 Recombinant Protein – Cat# MBS1476275

Cysteine-Rich Hydrophobic Domain 2 Protein (CHIC2) Human Recombinant Protein

Name: CHIC2 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1476275
Price: 455 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1476275

MBS1476275 is a recombinant protein targeting CHIC2. Also known as Recombinant Human Cysteine-rich hydrophobic domain 2 protein (CHIC2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$455 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cysteine-rich hydrophobic domain 2 protein (CHIC2), Recombinant Protein

Full Product Name

Recombinant Human Cysteine-rich hydrophobic domain 2 protein (CHIC2)

Product Gene Name

CHIC2 recombinant protein

Product Synonym Gene Name

CHIC2; BTL

Product Synonym Names

Cysteine-rich hydrophobic domain 2 protein; BrX-like translocated in leukemia

Sequence

MADFDEIYEE EEDEERALEE QLLKYSPDPV VVRGSGHVTV FGLSNKFESE FPSSLTGKVA PEEFKASINR VNSCLKKNLP VNVRWLLCGC LCCCCTLGCS MWPVICLSKR TRRSIEKLLE WENNRLYHKL CLHWRLSKRK CETNNMMEYV ILIEFLPKTP IFRPD

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

46.3 kDa

Sequence Positions

1-165aa; Full Length

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

604332

3D Structure

ModBase 3D Structure for Q9UKJ5

Species

Homo sapiens (Human)

Tag information

N-terminal GST-tagged.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CHIC2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CHIC2. It may not necessarily be applicable to this product.

NCBI GI #

6912276

NCBI GeneID

26511

NCBI Accession #

NP_036242.1

UniProt Primary Accession #

Q9UKJ5

UniProt Secondary Accession #

B2R639

UniProt Related Accession #

Q9UKJ5

GenBank Nucleotide #

NM_012110.3

NCBI Official Full Name

cysteine-rich hydrophobic domain-containing protein 2

NCBI Official Synonym Full Names

cysteine-rich hydrophobic domain 2

NCBI Official Symbol

CHIC2

NCBI Official Synonym Symbols

BTL

UniProt Protein Name

Cysteine-rich hydrophobic domain-containing protein 2

UniProt Synonym Protein Names

BrX-like translocated in leukemia

Protein Family

Cysteine-rich hydrophobic domain-containing protein

UniProt Gene Name

CHIC2

UniProt Synonym Gene Names

BTL

UniProt Entry Name

CHIC2_HUMAN

NCBI Protein Information

cysteine-rich hydrophobic domain-containing protein 2; BRX-like translocated in leukemia; cystein-rich hydrophobic domain 2; cysteine-rich hydrophobic domain 2 protein

NCBI Summary for CHIC2

This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008]

UniProt Comments for CHIC2

CHIC2: A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6. Belongs to the CHIC family.

Chromosomal Location of Human Ortholog: 4q11

Cellular Component: plasma membrane; Golgi-associated vesicle

Molecular Function: protein binding

Biological Process: Golgi to plasma membrane transport

Disease: Leukemia, Acute Myeloid

Research Articles on CHIC2

1. studied a new FISH method to detect CHIC2 deletion, FIP1L1/PDGFRA fusion and PDGFRA translocation in patients with myeloid neoplasms associated with eosinophilia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CHIC2 recombinant protein

Reference Product	PubMed Publications
PDGFRA recombinant protein	>10 publications with CHIC2 and PDGFRA
FIP1L1 recombinant protein	>10 publications with CHIC2 and FIP1L1
KIT recombinant protein	>3 publications with CHIC2 and KIT
ETV6 recombinant protein	>2 publications with CHIC2 and ETV6

Diseases associated with CHIC2 recombinant protein

Disease Name	Pubmed Publications
Leukemia, Myeloid, Acute Antibodies	>3 publications with CHIC2 and Leukemia, Myeloid, Acute
Hypertension Antibodies	>1 publications with CHIC2 and Hypertension
Disease Models, Animal Antibodies	>1 publications with CHIC2 and Disease Models, Animal
Cardiomyopathies Antibodies	>1 publications with CHIC2 and Cardiomyopathies
Pain Antibodies	>1 publications with CHIC2 and Pain
Heart Diseases Antibodies	>1 publications with CHIC2 and Heart Diseases
Nervous System Diseases Antibodies	>1 publications with CHIC2 and Nervous System Diseases

Organs/Tissues associated with CHIC2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>7 publications with CHIC2 and Blood
Bone Antibodies	>6 publications with CHIC2 and Bone
Bone Marrow Antibodies	>6 publications with CHIC2 and Bone Marrow
Lung Antibodies	>1 publications with CHIC2 and Lung
Brain Antibodies	>1 publications with CHIC2 and Brain