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Afadin- and Alpha-Actinin-Binding Protein (SSX2IP) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1478126

This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple… More details

$1425 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Afadin- and alpha-actinin-binding protein (Ssx2ip), Recombinant Protein
Full Product Name
Recombinant Mouse Afadin- and alpha-actinin-binding protein (Ssx2ip)
Product Gene Name
Ssx2ip recombinant protein
Product Synonym Gene Name
Ssx2ip
Sequence
MGDWMTVTDP VLCTENKNLS QYTSETKMSP SSLYSQQVLC SSVPLSKNVH GVFGVFCTGE NIEQSISYLD QELTTFGFPS LYEESKSKEA KRELNIVAVL NCMNELLVLQ RKNLLAQESV ETQNLKLGSD MDHLQSCYAK LKEQLETSRR EMIGLQERDR QLQCKNRSLH QLLKNEKDEV QKLQNIIASR ATQYNHDVKR KEREYNKLKE RLHQLVMNKK DKNIAMDVLN YVGRADGKRG SWRTDKTEAR NEDEMYKILL NDYEYRQKQI LMENAELKKV LQQMKKEMIS LLSPQKKKPR ERAEDGTGTV AISDIEDDSG ELSRDSVWGL SCDTVREQLT NSIRKQWRIL KSHVEKLDNQ ASKVHSEGLN EEDVISRQDH EQETEKLELE IERCKEMIKA QQQLLQQQLA TTCDDDTTSL LRDCYLLEEK ERLKEEWTLF KEQKKNFERE RRSFTEAAIR LGLERKAFEE ERASWVKQQF LNMTNFDHQN SENVKLFSAF SGSSDPDNLI VHSRPRQKKL HSVANGVPAC TSKLTKSLPA SPSTSDFRQT HSCVSEHSSI SVLNITPEES KPSEVAREST DQKWSVQSRP SSREGCYSGC SSAFRSAHGD RDDLP
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
70,956 Da
Sequence Positions
1-615, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8VC66
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ssx2ip recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ssx2ip purchase

MBS1478126 is a recombinant protein targeting Ssx2ip. Also known as Recombinant Mouse Afadin- and alpha-actinin-binding protein (Ssx2ip). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Ssx2ip. It may not necessarily be applicable to this product.

NCBI GI #
359338985
NCBI GeneID
99167
NCBI Accession #
NP_001240697.1
UniProt Primary Accession #
Q8VC66
UniProt Secondary Accession #
Q8BG59; Q8C7X0; Q8K2F7
UniProt Related Accession #
Q8VC66
GenBank Nucleotide #
NM_001253768.2
NCBI Official Full Name
afadin- and alpha-actinin-binding protein isoform b
NCBI Official Synonym Full Names
synovial sarcoma, X 2 interacting protein
NCBI Official Symbol
Ssx2ip
NCBI Official Synonym Symbols
Adip; AU014939; AU042321
UniProt Protein Name
Afadin- and alpha-actinin-binding protein
UniProt Synonym Protein Names
Afadin DIL domain-interacting protein
Protein Family
Afadin- and alpha-actinin-binding protein
UniProt Gene Name
Ssx2ip
UniProt Synonym Gene Names
ADIP
NCBI Protein Information
afadin- and alpha-actinin-binding protein

UniProt Comments for Ssx2ip

Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (PubMed:12446711). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (PubMed:22027834). Involved in ciliogenesis (). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia ().
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Research Articles on Ssx2ip

1. The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Ssx2ip recombinant protein

 Products by Pathway  Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram

Diseases associated with Ssx2ip recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with Ssx2ip and Neoplasms
 Inflammation Antibodies  >1 publications with Ssx2ip and Inflammation

Organs/Tissues associated with Ssx2ip recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >3 publications with Ssx2ip and Testis
 Intestine Antibodies  >1 publications with Ssx2ip and Intestine
 Bone Marrow Antibodies  >1 publications with Ssx2ip and Bone Marrow
 Bone Antibodies  >1 publications with Ssx2ip and Bone
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