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P2RY4 Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS001479

MBS001479 is an antibody targeting P2RY4. Also known as Rabbit P2RY4 Antibody. Reactive in Human, mouse, rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
P2RY4, Antibody
Full Product Name
Rabbit P2RY4 Antibody
Product Gene Name
anti-P2RY4 antibody
Host
Rabbit
Species Reactivity
Human, mouse, rat
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Molecular Weight
40,963 Da
Chromosome Location
Chromosome: X; NC_000023.10 (69478016..69479654, complement). Location: Xq13
OMIM
300038
3D Structure
ModBase 3D Structure for P51582
Applications Tested/Suitable for anti-P2RY4 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-P2RY4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for P2RY4. It may not necessarily be applicable to this product.

NCBI GI #
4505561
NCBI GeneID
5030
NCBI Accession #
NP_002556.1
UniProt Primary Accession #
P51582
UniProt Secondary Accession #
Q4VBB7; Q4VBB8; Q502W2; Q5JT22
UniProt Related Accession #
P51582
GenBank Nucleotide #
NM_002565.3
NCBI Official Full Name
P2Y purinoceptor 4
NCBI Official Synonym Full Names
pyrimidinergic receptor P2Y, G-protein coupled, 4
NCBI Official Symbol
P2RY4
NCBI Official Synonym Symbols
NRU; P2P; UNR; P2Y4
UniProt Protein Name
P2Y purinoceptor 4
UniProt Synonym Protein Names
P2P; Uridine nucleotide receptor
Protein Family
P2Y purinoceptor
UniProt Gene Name
P2RY4
UniProt Synonym Gene Names
NRU; P2Y4; UNR
UniProt Entry Name
P2RY4_HUMAN
NCBI Protein Information
P2Y purinoceptor 4; uridine nucleotide receptor

NCBI Summary for P2RY4

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. [provided by RefSeq, Jul 2008]
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UniProt Comments for P2RY4

P2RY4: Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: Xq13

Cellular Component: basolateral plasma membrane; integral to plasma membrane; apical plasma membrane; plasma membrane

Molecular Function: purinergic nucleotide receptor activity, G-protein coupled; UTP-activated nucleotide receptor activity; ATP binding; uridine nucleotide receptor activity

Biological Process: elevation of cytosolic calcium ion concentration; transepithelial chloride transport; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
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Research Articles on P2RY4

1. show that P2 receptors and protein kinases are also involved in regulating injury-induced expression and the release of TSP-1 in injured astrocytes

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-P2RY4 antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Nucleotide GPCRs Pathway antibodies  Nucleotide GPCRs Pathway Diagram
 Nucleotide-like (purinergic) Receptors Pathway antibodies  Nucleotide-like (purinergic) Receptors Pathway Diagram
 P2Y Receptors Pathway antibodies  P2Y Receptors Pathway Diagram
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