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Secreted Frizzled-Related Protein 4 (SFRP4) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1479061

Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in… More details

$1040 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Secreted frizzled-related protein 4 (Sfrp4), Recombinant Protein
Full Product Name
Recombinant Rat Secreted frizzled-related protein 4 (Sfrp4)
Product Gene Name
Product Synonym Gene Name
Sfrp4
Sequence
VRGAPCEAVR IPMCRHMPWN ITRMPNHLHH STQENAILAI EQYEELVDVN CSSVLRFFLC AMYAPICTLE FLHDPIKPCK SVCQRARDDC EPLMKMYNHS WPESLACDEL PVYDRGVCIS PEAIVTDLPE DVKWIDITPD MMVQERSFDA DCKHLSPDRC KCKKVKPTLA TYLSKNYSYV IHAKIKAVQR SGCNEVTTVV DVKEIFKSSS PIPRTQVPLI TNSSCQCPHI LPHQDVLIMC YERRSRMMLL ENCLVEKWRD QLSRRSTQWE ERLQEQQRTT QDKKQIASRT SRSNPPKPKG RSPASKPASP KKNIKARSAP KKSNPKKSTS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
39,762 Da
Sequence Positions
19-348, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9JLS4
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Sfrp4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sfrp4 purchase

MBS1479061 is a recombinant protein targeting Sfrp4. Also known as Recombinant Rat Secreted frizzled-related protein 4 (Sfrp4). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Sfrp4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
secreted frizzled-related protein 4
NCBI Official Synonym Full Names
secreted frizzled-related protein 4
NCBI Official Symbol
Sfrp4
UniProt Protein Name
Secreted frizzled-related protein 4
UniProt Synonym Protein Names
DDC-4 protein
UniProt Gene Name
Sfrp4
UniProt Synonym Gene Names
Ddc4; Frp; sFRP-4
NCBI Protein Information
secreted frizzled-related protein 4

NCBI Summary for Sfrp4

Wnt binding protein involved in modulation of Wnt signaling [RGD, Feb 2006]

UniProt Comments for Sfrp4

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (). SFRP4 plays a role in bone morphogenesis (). May also act as a regulator of adult uterine morphology and function (PubMed:12063187). May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (PubMed:12960062). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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