Epstein-Barr Virus EBNA1 Recombinant Protein – Cat# MBS1479282

Epstein-Barr Nuclear Antigen 1 (EBNA1) Epstein-Barr Virus Recombinant Protein

Name: EBNA1 Recombinant Protein; Epstein-Barr Virus; MyBioSource
Brand: MyBioSource
SKU: MBS1479282
Price: 275 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1479282

MBS1479282 is a recombinant protein targeting EBNA1. Also known as Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 1 (EBNA1), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$275 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Epstein-Barr nuclear antigen 1 (EBNA1), Recombinant Protein

Full Product Name

Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 1 (EBNA1), partial

Product Gene Name

EBNA1 recombinant protein

Product Synonym Gene Name

EBNA1

Sequence

RRKKGGWYGK HRGEGGSSQK FENIAEGLRL LLARCHVERT TEDGNWVAGV FVYGGSKTSL YNLRRGIGLA IPQCRLTPLS RLPFGMAPGP GPQPGPLRES IVCYFIVFLQ THIFAEGLKD AIKDLVLPKP APTCNIKVTV CSFDDGVDLP PWFPPMVEGA AAEGDDGDDG DEGGDGDEGE EGQE

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

56,496 Da

Sequence Positions

458-641aa, Partial-length

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q1HVF7

Species

Epstein-Barr virus (strain AG876) (HHV-4) (Human herpesvirus 4)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of EBNA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EBNA1. It may not necessarily be applicable to this product.

NCBI GI #

139424506

NCBI GeneID

5176225

NCBI Accession #

YP_001129471.1

UniProt Primary Accession #

Q1HVF7

GenBank Nucleotide #

NC_009334.1

NCBI Official Full Name

EBNA-1

NCBI Official Symbol

HHV4tp2_gp36

UniProt Protein Name

Epstein-Barr nuclear antigen 1

Protein Family

Epstein-Barr nuclear antigen

UniProt Gene Name

EBNA1

UniProt Synonym Gene Names

EBNA-1; EBV nuclear antigen 1

NCBI Protein Information

latency protein

UniProt Comments for EBNA1

Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase, the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication, oriP. Additionally, it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally, it can counteract the stabilization of host p53/TP53 by host USP7, thereby decreasing apoptosis and increasing host cell survival ().

Research Articles on EBNA1

1. PARP1-dependent PARylation of EBNA1 and adjacently bound TRF2 induces structural changes at the dyad symmetry element that reduce EBNA1 DNA binding affinity and functional recruitment of origin recognition complex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.