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Methionine Synthase Reductase (MTRR) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1479576

Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor.… More details

$1545 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Methionine synthase reductase (Mtrr), Recombinant Protein
Full Product Name
Recombinant Rat Methionine synthase reductase (Mtrr)
Product Gene Name
Product Synonym Gene Name
Mtrr
Sequence
MRRFLLLYAT QRGQAKAIAE EISEQALSHG FSADLHCVSE SEKYDLKTET GPLVMVVSTT GTGDPPDTAR KFVKEIHNKT LPTDFFAHLW YGLLGLGDSE YTYFCNGGKV IDKRLQELGA QHFYDTGHAD DCVGLELVVE PWIDGLWPAL TKHFKSLGGQ EDMSDSDTLA QASDAPLSMA MKPELLHIQS QVELLSLEDV GKRDSELQEQ NETNKNQPSR IEDFDSSLVN SVPPLSQSSL SIPAVSPEYL EVYLQESLGQ DENQASVPPS VDPIFQVPIS KAVELTTNDA IKTTLLLELD ISKVEFSHQP GDSFNVICPN SGSEVEDLLQ RLQLADKQAH RVILKIKMDT KKKGASLPQH VPEGSSLQFI FTWCLEIRAV PKKAFLRALS DYTSDATEKR RLQELCSKQG AADYNRFIRD ASVCLLDLLL TFPSCQPPLN LLLEHLPKLQ PRPYSCASSS LLHPDKLHFV FNIVELPSNT TAASLRKGVC TGWLATLVAP FLQPNTEVLT ADHSDALAPE ILISPRATNS FHLPDDLSAP IIMVGPGTGV APFVGFLQHR EKLQEQHPDG NFGAMWLFFG CRHKDRDYLF REELRHFLKT GVLTHLKVSF SRDAAPEEEE EAPAKYVQDN LQHHSQQVAR TLLQENGYIY VCGDAKNMAK DVHDALVEII SKEAGVDKLE AMKTLATLKQ EKRYLQDIWS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
56,531 Da
Sequence Positions
1-700, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q498R1
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mtrr recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mtrr purchase

MBS1479576 is a recombinant protein targeting Mtrr. Also known as Recombinant Rat Methionine synthase reductase (Mtrr). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Mtrr. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
methionine synthase reductase
NCBI Official Synonym Full Names
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NCBI Official Symbol
Mtrr
NCBI Official Synonym Symbols
MSR
UniProt Protein Name
Methionine synthase reductase
UniProt Gene Name
Mtrr
UniProt Synonym Gene Names
MSR
NCBI Protein Information
methionine synthase reductase

UniProt Comments for Mtrr

Involved in the reductive regeneration of cob(I)alamin (vitamin B12) cofactor required for the maintenance of methionine synthase in a functional state. Necessary for utilization of methylgroups from the folate cycle, thereby affecting transgenerational epigenetic inheritance. Folate pathway donates methyl groups necessary for cellular methylation and affects different pathways such as DNA methylation, possibly explaining the transgenerational epigenetic inheritance effects ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Mtrr recombinant protein

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