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Vacuolar Protein-Sorting-Associated Protein 36 (VPS36) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1480161

MBS1480161 is a recombinant protein targeting Vps36. Also known as Recombinant Mouse Vacuolar protein-sorting-associated protein 36 (Vps36). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1120 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Vacuolar protein-sorting-associated protein 36 (Vps36), Recombinant Protein
Full Product Name
Recombinant Mouse Vacuolar protein-sorting-associated protein 36 (Vps36)
Product Gene Name
Vps36 recombinant protein
Product Synonym Gene Name
Vps36
Sequence
MDRFVWTSGL LEINETLVIQ QRGVRVYDGE EKIKFDAGTL LLSTHRLIWR DQKNNECCMA IPLSQIVFIE EQAAGIGKSA KIVVHLHPAP SNKEPGPFQS SKNSYIRLSF KEHGQIEFYR RLSEEMTQRR WETVPVSQSL QTNKGPQPGR VRAVGIVGIE RKLEEKRKET DKNISEAFED LSKLMIKAKE MVELSKSIAN KIKEKQGDVT EDETIRFKSY LLSMGIANPV TRETYGSGTQ YHMQLAKQLA GILQAPLEER GGIMSLTEVY CLVNRARGME LLSPEDLVNA CKMLEALKLP IRLRVFDSGV MVIELQTHKE EEMVASALET VSERGSLTSE EFAKLVGMSV LLAKERLLLA EKMGHLCRDD SVEGLRFYPN LFMTQN
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
43,736 Da
Sequence Positions
1-386, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q91XD6
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Vps36 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Vps36. It may not necessarily be applicable to this product.

NCBI GI #
30794416
NCBI GeneID
70160
NCBI Accession #
NP_081614.1
UniProt Primary Accession #
Q91XD6
UniProt Secondary Accession #
Q9CVA3
UniProt Related Accession #
Q91XD6
GenBank Nucleotide #
NM_027338.1
NCBI Official Full Name
vacuolar protein-sorting-associated protein 36
NCBI Official Synonym Full Names
vacuolar protein sorting 36
NCBI Official Symbol
Vps36
NCBI Official Synonym Symbols
Eap45; 1700010A24Rik; 2210415M20Rik; 2810408E15Rik
UniProt Protein Name
Vacuolar protein-sorting-associated protein 36
UniProt Synonym Protein Names
ESCRT-II complex subunit VPS36
Protein Family
Vacuolar protein sorting-associated protein
UniProt Gene Name
Vps36
NCBI Protein Information
vacuolar protein-sorting-associated protein 36

UniProt Comments for Vps36

Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.
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Research Articles on Vps36

1. presentation of the complex structure of Eap45 GLUE and ubiquitin at 3.35 A resolution, which explains the previously uncharacterized mechanism of Ub recognition by mammalian ESCRT-II

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Vps36 recombinant protein

 Products by Pathway  Pathway Diagram
 ESCRT-II Complex Pathway antibodies  ESCRT-II Complex Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram

Diseases associated with Vps36 recombinant protein

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >2 publications with Vps36 and Kidney Diseases
 Congenital Abnormalities Antibodies  >1 publications with Vps36 and Congenital Abnormalities
 Death Antibodies  >1 publications with Vps36 and Death

Organs/Tissues associated with Vps36 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with Vps36 and Blood
 Kidney Antibodies  >2 publications with Vps36 and Kidney
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