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Ran-Binding Protein 10 (RANBP10) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1481180

MBS1481180 is a recombinant protein targeting RANBP10. Also known as Recombinant Human Ran-binding protein 10 (RANBP10). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1430 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ran-binding protein 10 (RANBP10), Recombinant Protein
Full Product Name
Recombinant Human Ran-binding protein 10 (RANBP10)
Product Gene Name
RANBP10 recombinant protein
Product Synonym Gene Name
RANBP10
Sequence
AAATADPGAG NPQPGDSSGG GAGGGLPSPG EQELSRRLQR LYPAVNQQET PLPRSWSPKD KYNYIGLSQG NLRVHYKGHG KNHKDAASVR ATHPIPAACG IYYFEVKIVS KGRDGYMGIG LSAQGVNMNR LPGWDKHSYG YHGDDGHSFC SSGTGQPYGP TFTTGDVIGC CVNLINGTCF YTKNGHSLGI AFTDLPANLY PTVGLQTPGE IVDANFGQQP FLFDIEDYMR EWRAKVQGTV HCFPISARLG EWQAVLQNMV SSYLVHHGYC ATATAFARMT ETPIQEEQAS IKNRQKIQKL VLEGRVGEAI ETTQRFYPGL LEHNPNLLFM LKCRQFVEMV NGTDSEVRSL SSRSPKSQDS YPGSPSLSPR HGPSSSHMHN TGADSPSCSN GVASTKSKQN HSKYPAPSSS SSSSSSSSSS SPSSVNYSES NSTDSTKSQH HSSTSNQETS DSEMEMEAEH YPNGVLGSMS TRIVNGAYKH EDLQTDESSM DDRHPRRQLC GGNQAATERI ILFGRELQAL SEQLGREYGK NLAHTEMLQD AFSLLAYSDP WSCPVGQQLD PIQREPVCAA LNSAILESQN LPKQPPLMLA LGQASECLRL MARAGLGSCS FARVDDYLH
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
64,542 Da
Sequence Positions
2-620, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
614031
3D Structure
ModBase 3D Structure for Q6VN20
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RANBP10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RANBP10. It may not necessarily be applicable to this product.

NCBI GI #
998074446
NCBI GeneID
57610
NCBI Accession #
NP_001307167.1
UniProt Primary Accession #
Q6VN20
UniProt Secondary Accession #
Q9P264; A4FTY2; B4DID0; B4DQH9; E7EW27
UniProt Related Accession #
Q6VN20
GenBank Nucleotide #
NM_001320238.1
NCBI Official Full Name
ran-binding protein 10 isoform 2
NCBI Official Synonym Full Names
RAN binding protein 10
NCBI Official Symbol
RANBP10
UniProt Protein Name
Ran-binding protein 10
Protein Family
Ran-binding protein
UniProt Gene Name
RANBP10
UniProt Synonym Gene Names
KIAA1464; RanBP10
NCBI Protein Information
ran-binding protein 10

NCBI Summary for RANBP10

RAN is a small GTPase involved in the assembly of microtubules to form mitotic spindles. The protein encoded by this gene is a cytoplasmic guanine nucleotide exchange factor (GEF) that binds beta-tubulin and has GEF activity toward RAN. The encoded protein plays a role in the formation of noncentrosomal microtubules. In addition, this protein may be involved in the regulation of D(1) receptor signaling by protein kinase C delta and protein kinase C gamma. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
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UniProt Comments for RANBP10

Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function (). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. In contrast to RANBP9, does not interact with Sos and does not activate the Ras pathway.
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Research Articles on RANBP10

1. The results showed that ICP0 interacted with cell protein RanBP10, a known transcriptional coactivator, in human herpesvirus 1-infected cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RANBP10 recombinant protein

 Reference Product  PubMed Publications
 RAN recombinant protein  >6 publications with RANBP10 and RAN
 MET recombinant protein  >2 publications with RANBP10 and MET

Pathways associated with RANBP10 recombinant protein

 Products by Pathway  Pathway Diagram
 Signaling Events Mediated By Hepatocyte Growth Factor Receptor (c-Met) Pathway antibodies  Signaling Events Mediated By Hepatocyte Growth Factor Receptor (c-Met) Pathway Diagram

Diseases associated with RANBP10 recombinant protein

 Disease Name  Pubmed Publications
 Stroke Antibodies  >1 publications with RANBP10 and Stroke
 Immune System Diseases Antibodies  >1 publications with RANBP10 and Immune System Diseases

Organs/Tissues associated with RANBP10 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with RANBP10 and Nerve
 Liver Antibodies  >1 publications with RANBP10 and Liver
 Kidney Antibodies  >1 publications with RANBP10 and Kidney
 Prostate Antibodies  >1 publications with RANBP10 and Prostate
 Embryonic Tissue Antibodies  >1 publications with RANBP10 and Embryonic Tissue
 Uterus Antibodies  >1 publications with RANBP10 and Uterus
 Brain Antibodies  >1 publications with RANBP10 and Brain
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