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TNFAIP3-Interacting Protein 2 (TNIP2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1484241

MBS1484241 is a recombinant protein targeting Tnip2. Also known as Recombinant Mouse TNFAIP3-interacting protein 2 (Tnip2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1185 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TNFAIP3-interacting protein 2 (Tnip2), Recombinant Protein
Full Product Name
Recombinant Mouse TNFAIP3-interacting protein 2 (Tnip2)
Product Gene Name
Tnip2 recombinant protein
Product Synonym Gene Name
Tnip2
Sequence
MSSGDPRSGR QDGAPRAAAA LCGLYHEAGQ QLQRLKDQLA ARDALIASLR TRLAALEGHT APSLVDALLD QVERFREQLR RQEEGASETQ LRQEVERLTE RLEEKEREMQ QLMSQPQHEQ EKEVVLLRRS VAEKEKARAA SDVLCRSLAD ETHQLRRTLA ATAHMCQHLA KCLDERQCAQ GDAGEKSPAE LEQTSSDASG QSVIKKLQEE NRLLKQKVTH VEDLNAKWQR YDASRDEYVK GLHAQLKRRQ VPLEPELMKK EISRLNRQLE EKISDCAEAN QELTAMRMSR DTALERVQML EQQILAYKDD FKSERADRER AHSRIQELEE KIMSLMYQVS QRQDSREPGP CRIHTGNKTA KYLEMDALEH VTPGGWRPES RSQQMEPSAE GGHVCTAQRG QGDLQCPHCL RCFSDEQGEA FLRHLSECCQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
49,094 Da
Sequence Positions
1-430, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q99JG7
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Tnip2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Tnip2. It may not necessarily be applicable to this product.

NCBI GI #
20532344
NCBI GeneID
231130
NCBI Accession #
NP_620703.1
UniProt Primary Accession #
Q99JG7
UniProt Secondary Accession #
Q3TVF3
UniProt Related Accession #
Q99JG7
GenBank Nucleotide #
NM_139064.2
NCBI Official Full Name
TNFAIP3-interacting protein 2
NCBI Official Synonym Full Names
TNFAIP3 interacting protein 2
NCBI Official Symbol
Tnip2
NCBI Official Synonym Symbols
ABIN-2; AI428870; 1810020H16Rik
UniProt Protein Name
TNFAIP3-interacting protein 2
UniProt Synonym Protein Names
A20-binding inhibitor of NF-kappa-B activation 2; ABIN-2
Protein Family
TNFAIP3-interacting protein
UniProt Gene Name
Tnip2
UniProt Synonym Gene Names
ABIN-2
NCBI Protein Information
TNFAIP3-interacting protein 2

UniProt Comments for Tnip2

Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes.
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Research Articles on Tnip2

1. ABIN-2 acts as a positive regulator of NF-kappaB-dependent transcription by activating IKKalpha.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Tnip2 recombinant protein

 Products by Pathway  Pathway Diagram
 TNF-alpha NF-kB Signaling Pathway antibodies  TNF-alpha NF-kB Signaling Pathway Diagram

Diseases associated with Tnip2 recombinant protein

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >13 publications with Tnip2 and Necrosis
 Fetal Death Antibodies  >2 publications with Tnip2 and Fetal Death
 Retinoblastoma Antibodies  >1 publications with Tnip2 and Retinoblastoma
 Fibrosarcoma Antibodies  >1 publications with Tnip2 and Fibrosarcoma
 Proteinuria Antibodies  >1 publications with Tnip2 and Proteinuria
 Anemia Antibodies  >1 publications with Tnip2 and Anemia
 Colonic Neoplasms Antibodies  >1 publications with Tnip2 and Colonic Neoplasms
 Disease Models, Animal Antibodies  >1 publications with Tnip2 and Disease Models, Animal
 Pregnancy Complications Antibodies  >1 publications with Tnip2 and Pregnancy Complications
 Kidney Neoplasms Antibodies  >1 publications with Tnip2 and Kidney Neoplasms

Organs/Tissues associated with Tnip2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with Tnip2 and Liver
 Bone Antibodies  >2 publications with Tnip2 and Bone
 Kidney Antibodies  >2 publications with Tnip2 and Kidney
 Bone Marrow Antibodies  >2 publications with Tnip2 and Bone Marrow
 Lung Antibodies  >1 publications with Tnip2 and Lung
 Lymph Node Antibodies  >1 publications with Tnip2 and Lymph Node
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