Human IFT27 Recombinant Protein – Cat# MBS1487761

Intraflagellar Transport Protein 27 Homolog (IFT27) Human Recombinant Protein

Name: IFT27 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1487761
Price: 455 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1487761

Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6. Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6.… More details

$455 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Intraflagellar transport protein 27 homolog (IFT27), Recombinant Protein

Full Product Name

Recombinant Human Intraflagellar transport protein 27 homolog

Product Gene Name

IFT27 recombinant protein

Product Synonym Names

Putative GTP-binding protein RAY-like; Rab-like protein 4

Sequence

MVKLAAKCIL AGDPAVGKTA LAQIFRSDGA HFQKSYTLTT GMDLVVKTVP VPDTGDSVEL FIFDSAGKEL FSEMLDKLWE SPNVLCLVYD VTNEESFNNC SKWLEKARSQ APGISLPGVL VGNKTDLAGR RAVDSAEARA WALGQGLECF ETSVKEMENF EAPFHCLAKQ FHQLYREKVE VFRALA

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Molecular Weight

36.5 kDa

Sequence Positions

1-186aa; Full Length

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

615870

3D Structure

ModBase 3D Structure for Q9BW83

Product Categories/Family for IFT27 recombinant protein

Signal Transduction

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for IFT27 recombinant protein

Reevaluating human gene annotation a second-generation analysis of chromosome 22.Collins J.E., Goward M.E., Cole C.G., Smink L.J., Huckle E.J., Knowles S., Bye J.M., Beare D.M., Dunham I.Genome Res. 13:27-36(2003)

Other Notes

Small volumes of IFT27 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IFT27 purchase

MBS1487761 is a recombinant protein targeting IFT27. Also known as Recombinant Human Intraflagellar transport protein 27 homolog. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for IFT27. It may not necessarily be applicable to this product.

NCBI GI #

295148109

NCBI GeneID

11020

NCBI Accession #

NP_001171172.1

UniProt Primary Accession #

Q9BW83

UniProt Secondary Accession #

O60897

UniProt Related Accession #

Q9BW83

GenBank Nucleotide #

NM_001177701.2

NCBI Official Full Name

intraflagellar transport protein 27 homolog isoform 1

NCBI Official Synonym Full Names

intraflagellar transport 27

NCBI Official Symbol

IFT27

NCBI Official Synonym Symbols

RAYL; BBS19; RABL4

UniProt Protein Name

Intraflagellar transport protein 27 homolog

UniProt Synonym Protein Names

Putative GTP-binding protein RAY-like; Rab-like protein 4

Protein Family

Intraflagellar transport protein

UniProt Gene Name

IFT27

UniProt Synonym Gene Names

RABL4; RAYL

UniProt Entry Name

IFT27_HUMAN

NCBI Protein Information

intraflagellar transport protein 27 homolog

NCBI Summary for IFT27

This gene encodes a GTP-binding protein that is a core component of the intraflagellar transport complex B. Characterization of the similar Chlamydomonas protein indicates a function in cell cycle control. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

UniProt Comments for IFT27

RABL4: Possesses GTPase activity. Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, monomeric; G protein, monomeric, Ras; G protein

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: centrosome; cilium

Molecular Function: GTP binding; protein binding

Biological Process: intracellular protein transport; intraflagellar transport; organelle organization and biogenesis; small GTPase mediated signal transduction; smoothened signaling pathway

Research Articles on IFT27

1. Study coupled human genetics with functional validation in zebrafish and identified IFT27 as a novel BBS gene (BBS19).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IFT27 recombinant protein

Reference Product	PubMed Publications
IFT46 recombinant protein	>4 publications with IFT27 and IFT46
IFT172 recombinant protein	>2 publications with IFT27 and IFT172
IFT81 recombinant protein	>2 publications with IFT27 and IFT81
IFT88 recombinant protein	>2 publications with IFT27 and IFT88
IFT52 recombinant protein	>2 publications with IFT27 and IFT52
HSPB11 recombinant protein	>1 publications with IFT27 and HSPB11

Pathways associated with IFT27 recombinant protein

Products by Pathway	Pathway Diagram
Assembly Of The Primary Cilium Pathway antibodies	Assembly Of The Primary Cilium Pathway Diagram
Intraflagellar Transport Pathway antibodies	Intraflagellar Transport Pathway Diagram
Organelle Biogenesis And Maintenance Pathway antibodies	Organelle Biogenesis And Maintenance Pathway Diagram

Diseases associated with IFT27 recombinant protein

Disease Name	Pubmed Publications
Hypertension Antibodies	>1 publications with IFT27 and Hypertension

Organs/Tissues associated with IFT27 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1 publications with IFT27 and Blood
Skin Antibodies	>1 publications with IFT27 and Skin
Kidney Antibodies	>1 publications with IFT27 and Kidney