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Sclerostin Domain-Containing Protein 1 (SOSTDC1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1488404

May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling By similarity. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a… More details

$230 / 0.05 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Sclerostin domain-containing protein 1 (SOSTDC1), Polyclonal Antibody
Full Product Name
Rabbit anti-human Sclerostin domain-containing protein 1 polyclonal Antibody, HRP conjugated
Product Gene Name
Product Synonym Names
Ectodermal BMP inhibitor Uterine sensitization-associated gene 1 protein SOSTDC1 USAG1 CDA019
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
26,260 Da
OMIM
609675
3D Structure
ModBase 3D Structure for Q6X4U4
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
HRP
Immunogen
Recombinant human Sclerostin domain-containing protein 1 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162253
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SOSTDC1 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-SOSTDC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SOSTDC1 purchase

MBS1488404 is an antibody targeting SOSTDC1. Also known as Rabbit anti-human Sclerostin domain-containing protein 1 polyclonal Antibody, HRP conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SOSTDC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sclerostin domain-containing protein 1
NCBI Official Synonym Full Names
sclerostin domain containing 1
NCBI Official Symbol
SOSTDC1
NCBI Official Synonym Symbols
USAG1; CDA019; ECTODIN
UniProt Protein Name
Sclerostin domain-containing protein 1
UniProt Synonym Protein Names
Ectodermal BMP inhibitor; Ectodin; Uterine sensitization-associated gene 1 protein; USAG-1
UniProt Gene Name
SOSTDC1
UniProt Synonym Gene Names
USAG1; Ectodin; USAG-1
UniProt Entry Name
SOSD1_HUMAN
NCBI Protein Information
sclerostin domain-containing protein 1

NCBI Summary for SOSTDC1

This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]
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UniProt Comments for SOSTDC1

SOSTDC1: May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. Belongs to the sclerostin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 7p21.1

Cellular Component: extracellular space

Biological Process: hair follicle morphogenesis; negative regulation of BMP signaling pathway; negative regulation of cell fate commitment; odontogenesis of dentine-containing teeth; pattern specification process; Wnt receptor signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SOSTDC1 antibody

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