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Glucagon-Like Peptide 1 Receptor (GLP1R) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1489833

This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glucagon-like peptide 1 receptor (GLP1R), Polyclonal Antibody
Full Product Name
Rabbit anti-human Glucagon-like peptide 1 receptor polyclonal Antibody, HRP conjugated
Product Gene Name
anti-GLP1R antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: GLP1R (MBS7002318)
HRP Conjugated Antibody: GLP1R (MBS1489833)
Molecular Weight
53,026 Da
OMIM
138032
3D Structure
ModBase 3D Structure for P43220
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
HRP
Immunogen
Recombinant human Glucagon-like peptide 1 receptor protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34637 / sc-66911
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GLP1R antibody
ELISA (EIA)

Western Blot (WB) of anti-GLP1R antibody

All lanes: Glucagon-like peptide 1 receptor antibody at 2ug/ml+293T whole cell lysate secondary Goat polyclonal to rabbit at 1/10000 dilution predicted band size:53kDa observed band size:53kDa Immunohistochemistry
Rabbit Anti-GLP1R Polyclonal Antibody – Cat# MBS1489833

Immunohistochemistry (IHC) of anti-GLP1R antibody

Immunohistochemistry of paraffin-embedded human pancreas at dilution 1:100
Rabbit Anti-GLP1R Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1489833

Other Notes

Small volumes of anti-GLP1R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GLP1R purchase

MBS1489833 is an antibody targeting GLP1R. Also known as Rabbit anti-human Glucagon-like peptide 1 receptor polyclonal Antibody, HRP conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GLP1R. It may not necessarily be applicable to this product.

NCBI GI #
166795283
NCBI GeneID
2740
NCBI Accession #
NP_002053.3
UniProt Primary Accession #
P43220
UniProt Secondary Accession #
Q2M229; Q99669
UniProt Related Accession #
P43220
GenBank Nucleotide #
NM_002062.3
NCBI Official Full Name
glucagon-like peptide 1 receptor
NCBI Official Synonym Full Names
glucagon like peptide 1 receptor
NCBI Official Symbol
GLP1R
UniProt Protein Name
Glucagon-like peptide 1 receptor
Protein Family
Glucagon-like peptide 1 receptor
UniProt Gene Name
GLP1R
UniProt Synonym Gene Names
GLP-1 receptor; GLP-1-R; GLP-1R
UniProt Entry Name
GLP1R_HUMAN
NCBI Protein Information
glucagon-like peptide 1 receptor

UniProt Comments for GLP1R

GLP1R: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: Receptor, GPCR; GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p21

Cellular Component: cytosol; integral to membrane; intracellular; plasma membrane

Molecular Function: glucagon receptor activity; protein binding; transmembrane receptor activity

Biological Process: adenylate cyclase activation; cAMP-mediated signaling; cell surface receptor linked signal transduction; elevation of cytosolic calcium ion concentration; energy reserve metabolic process; G-protein coupled receptor protein signaling pathway; learning and/or memory; positive regulation of blood pressure; regulation of heart contraction; regulation of insulin secretion; response to stress
Show more

Research Articles on GLP1R

1. a novel GLP1R Interacting Protein ATP6ap2

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GLP1R antibody

 Reference Product  PubMed Publications
 GIP antibody  >100 publications with GLP1R and GIP
 DPP4 antibody  >59 publications with GLP1R and DPP4
 INS antibody  >48 publications with GLP1R and INS
 POMC antibody  >14 publications with GLP1R and POMC
 VIP antibody  >12 publications with GLP1R and VIP
 GCG antibody  >10 publications with GLP1R and GCG
 IAPP antibody  >6 publications with GLP1R and IAPP
 MC4R antibody  >5 publications with GLP1R and MC4R
 PTH antibody  >3 publications with GLP1R and PTH
 NPS antibody  >1 publications with GLP1R and NPS

Pathways associated with anti-GLP1R antibody

 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Glucagon-like Peptide-1 (GLP1) Regulates Insulin Secretion Pathway antibodies  Glucagon-like Peptide-1 (GLP1) Regulates Insulin Secretion Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Insulin Secretion Pathway antibodies  Insulin Secretion Pathway Diagram
 Integration Of Energy Metabolism Pathway antibodies  Integration Of Energy Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram

Diseases associated with anti-GLP1R antibody

 Disease Name  Pubmed Publications
 Weight Loss Antibodies  >165 publications with GLP1R and Weight Loss
 Hyperglycemia Antibodies  >146 publications with GLP1R and Hyperglycemia
 Hypoglycemia Antibodies  >142 publications with GLP1R and Hypoglycemia
 Disease Models, Animal Antibodies  >121 publications with GLP1R and Disease Models, Animal
 Insulin Resistance Antibodies  >112 publications with GLP1R and Insulin Resistance
 Diabetes Mellitus, Experimental Antibodies  >94 publications with GLP1R and Diabetes Mellitus, Experimental
 Weight Gain Antibodies  >80 publications with GLP1R and Weight Gain
 Vascular Diseases Antibodies  >77 publications with GLP1R and Vascular Diseases
 Inflammation Antibodies  >50 publications with GLP1R and Inflammation
 Heart Diseases Antibodies  >40 publications with GLP1R and Heart Diseases

Organs/Tissues associated with anti-GLP1R antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >180 publications with GLP1R and Brain
 Kidney Antibodies  >80 publications with GLP1R and Kidney
 Skin Antibodies  >6 publications with GLP1R and Skin
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