Fatty Acid-Binding Protein (FABPL) Antibody – Rabbit Polyclonal

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]

FABP1: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2p11

Cellular Component: apical cortex; cytoplasm; cytosol; nucleoplasm; peroxisomal matrix

Molecular Function: antioxidant activity; bile acid binding; chromatin binding; drug binding; fatty acid binding; long-chain fatty acid transporter activity; phospholipid binding; protein binding

Biological Process: cellular lipid metabolic process; intestinal absorption; long-chain fatty acid transport; negative regulation of apoptosis; negative regulation of caspase activity; positive regulation of cell proliferation; positive regulation of defense response to virus by host; positive regulation of fatty acid beta-oxidation; positive regulation of hydrolase activity; triacylglycerol catabolic process