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N-Acetylmuramoyl-L-Alanine Amidase (PGLYRP2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1490646

May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
N-acetylmuramoyl-L-alanine amidase (PGLYRP2), Polyclonal Antibody
Full Product Name
Rabbit anti-human N-acetylmuramoyl-L-alanine amidase polyclonal Antibody
Product Gene Name
anti-PGLYRP2 antibody
Product Synonym Names
N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) (Peptidoglycan recognition protein 2) (Peptidoglycan recognition protein long) (PGRP-L), PGLYRP2, PGLYRPL PGRPL
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: N-acetylmuramoyl-L-alanine amidase (MBS1490646)
Biotin Conjugated Antibody: N-acetylmuramoyl-L-alanine amidase (MBS1489066)
Matching Pairs
Unconjugated Antibody: N-acetylmuramoyl-L-alanine amidase (MBS1490646)
HRP Conjugated Antibody: N-acetylmuramoyl-L-alanine amidase (MBS1490805)
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Molecular Weight
68,000 Da
OMIM
608199
3D Structure
ModBase 3D Structure for Q96PD5
Species
Human
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant Human N-acetylmuramoyl-L-alanine amidase protein (22-576AA)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54941 / sc-54662 / sc-54943 / sc-50470
Research Area
Immunology
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PGLYRP2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-PGLYRP2 antibody
IHC: 1:20-1:200

Immunohistochemistry (IHC) of anti-PGLYRP2 antibody

Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS1490646 at dilution of 1:100
Rabbit Anti-PGLYRP2 Polyclonal Antibody – Cat# MBS1490646

Immunohistochemistry (IHC) of anti-PGLYRP2 antibody

Immunohistochemistry of paraffin-embedded human liver cancer using MBS1490646 at dilution of 1:100
Rabbit Anti-PGLYRP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1490646

Other Notes

Small volumes of anti-PGLYRP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PGLYRP2 purchase

MBS1490646 is an antibody targeting PGLYRP2. Also known as Rabbit anti-human N-acetylmuramoyl-L-alanine amidase polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PGLYRP2. It may not necessarily be applicable to this product.

NCBI GI #
156616294
NCBI GeneID
114770
NCBI Accession #
NP_443122.3
UniProt Primary Accession #
Q96PD5
UniProt Secondary Accession #
Q68CK1; Q96N74; Q9UC60; A8K050; A8K8C7; B2RMZ2; B7ZM33
UniProt Related Accession #
Q96PD5
GenBank Nucleotide #
NM_052890.3
NCBI Official Full Name
N-acetylmuramoyl-L-alanine amidase
NCBI Official Synonym Full Names
peptidoglycan recognition protein 2
NCBI Official Symbol
PGLYRP2
NCBI Official Synonym Symbols
tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha
UniProt Protein Name
N-acetylmuramoyl-L-alanine amidase
UniProt Synonym Protein Names
Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L
Protein Family
N-acetylmuramoyl-L-alanine amidase
UniProt Gene Name
PGLYRP2
UniProt Synonym Gene Names
PGLYRPL; PGRPL; PGRP-L
UniProt Entry Name
PGRP2_HUMAN
NCBI Protein Information
N-acetylmuramoyl-L-alanine amidase

NCBI Summary for PGLYRP2

This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]
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UniProt Comments for PGLYRP2

PGLYRP2: May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Receptor, misc.; Hydrolase; EC 3.5.1.28

Chromosomal Location of Human Ortholog: 19p13.12

Cellular Component: intracellular; membrane

Molecular Function: N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding; peptidoglycan receptor activity; zinc ion binding

Biological Process: defense response to Gram-positive bacterium; detection of bacterium; innate immune response; negative regulation of interferon-gamma production; negative regulation of natural killer cell differentiation during immune response; pattern recognition receptor signaling pathway; peptide amidation; peptidoglycan catabolic process; regulation of inflammatory response
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Research Articles on PGLYRP2

1. This study demonistrated that PGLYRP2 single-nucleotide polymorphisms is risk of Parkinson's disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PGLYRP2 antibody

 Reference Product  PubMed Publications
 NOD2 antibody  >5 publications with PGLYRP2 and NOD2
 JUN antibody  >4 publications with PGLYRP2 and JUN

Diseases associated with anti-PGLYRP2 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >9 publications with PGLYRP2 and Inflammation
 Edema Antibodies  >1 publications with PGLYRP2 and Edema
 Immune System Diseases Antibodies  >1 publications with PGLYRP2 and Immune System Diseases
 Nervous System Diseases Antibodies  >1 publications with PGLYRP2 and Nervous System Diseases
 Weight Loss Antibodies  >1 publications with PGLYRP2 and Weight Loss
 Hyperplasia Antibodies  >1 publications with PGLYRP2 and Hyperplasia
 Liver Diseases Antibodies  >1 publications with PGLYRP2 and Liver Diseases

Organs/Tissues associated with anti-PGLYRP2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with PGLYRP2 and Liver
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