Protein (AVPR1A) Antibody – Rabbit Polyclonal

This gene encodes a receptor for arginine vasopressin, a neurohypophyseal hormone involved in diuresis inhibition, smooth muscle contraction, liver glycogenolysis stimulation and regulation of adrenocorticotropic hormone release from the pituitary. This receptor represents one of three G protein-coupled arginine vasopressin receptors which functions through a phosphotidylinositol-calcium second messenger system in vascular and hepatic tissues. [provided by RefSeq, Jul 2008]

AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR

Cellular Component: cytoplasmic vesicle; cytoplasmic vesicle membrane; cytosol; integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: peptide hormone binding; V1A vasopressin receptor binding; vasopressin receptor activity

Biological Process: calcium-mediated signaling; cellular response to hormone stimulus; cellular response to water deprivation; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; grooming behavior; maternal behavior; myotube differentiation; negative regulation of female receptivity; negative regulation of transmission of nerve impulse; penile erection; positive regulation of blood pressure; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of cellular pH reduction; positive regulation of glutamate secretion; positive regulation of glycogen catabolic process; positive regulation of heart rate; positive regulation of prostaglandin biosynthetic process; positive regulation of systemic arterial blood pressure; positive regulation of vasoconstriction; regulation of adrenocorticotropin hormone secretion; regulation of systemic arterial blood pressure by vasopressin; response to corticosterone stimulus; response to inorganic substance; response to organic substance; social behavior; sperm ejaculation; telencephalon development