Guanine Nucleotide-Binding Protein G (GNAO) Antibody – Rabbit Polyclonal

G-alpha(o): Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14. Interacts with RGS14. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Belongs to the G-alpha family. G(i/o/t/z) subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein; G protein, heterotrimeric; G protein, heterotrimeric alpha G((i/o/t/z))

Cellular Component: dendrite; heterotrimeric G-protein complex; membrane; myelin sheath; neuron projection; plasma membrane; protein complex

Molecular Function: corticotropin-releasing hormone receptor 1 binding; G-protein beta/gamma-subunit binding; GTP binding; GTPase activating protein binding; GTPase activity; guanyl nucleotide binding; metabotropic serotonin receptor binding; metal ion binding; mu-type opioid receptor binding; nucleotide binding; protein binding; protein complex binding; signal transducer activity

Biological Process: aging; cellular process; dopamine receptor signaling pathway; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; locomotory behavior; negative regulation of calcium ion transport; positive regulation of GTPase activity; regulation of heart contraction; response to organic nitrogen; signal transduction