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Nicotinate Phosphoribosyltransferase (NAPRT) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1491066

Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nicotinate phosphoribosyltransferase (NAPRT), Polyclonal Antibody
Full Product Name
Rabbit anti-human Nicotinate phosphoribosyltransferase polyclonal Antibody
Product Gene Name
Product Synonym Names
Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21) (FHA-HITinteracting protein) (Nicotinate phosphoribosyltransferase domain-containing protein 1), NAPRT, FHIP NAPRT1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
OMIM
611552
3D Structure
ModBase 3D Structure for Q6XQN6
Immunogen
Recombinant Human Nicotinate phosphoribosyltransferase protein (1-310AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Research Area
Epigenetics and Nuclear Signaling
Target Names
NAPRT
Storage Buffer
Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-87326 / sc-87327
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NAPRT antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-NAPRT antibody
WB: 1:1000-1:5000

Western Blot (WB) of anti-NAPRT antibody

Western Blot
Positive WB detected in: HepG2 whole cell lysate, Mouse liver tissue, Mouse kidney tissue
All lanes: NAPRT antibody at 4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 58,61,57 kDa
Observed band size: 58 kDa
Rabbit Anti-NAPRT Polyclonal Antibody – Cat# MBS1491066

Other Notes

Small volumes of anti-NAPRT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NAPRT purchase

MBS1491066 is an antibody targeting NAPRT. Also known as Rabbit anti-human Nicotinate phosphoribosyltransferase polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NAPRT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nicotinate phosphoribosyltransferase isoform 2
NCBI Official Synonym Full Names
nicotinate phosphoribosyltransferase
NCBI Official Symbol
NAPRT
NCBI Official Synonym Symbols
NAPRT1; PP3856
UniProt Protein Name
Nicotinate phosphoribosyltransferase
UniProt Synonym Protein Names
FHA-HIT-interacting protein; Nicotinate phosphoribosyltransferase domain-containing protein 1
UniProt Gene Name
NAPRT
UniProt Synonym Gene Names
FHIP; NAPRT1; NAPRTase
UniProt Entry Name
PNCB_HUMAN
NCBI Protein Information
nicotinate phosphoribosyltransferase

NCBI Summary for NAPRT

Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008]
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UniProt Comments for NAPRT

NAPRT1: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. Belongs to the NAPRTase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.4.21; Transferase

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: cytoplasm; cytosol; Golgi apparatus; nucleus

Molecular Function: ligase activity; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; protein binding

Biological Process: NAD biosynthetic process; NAD metabolic process; nicotinamide metabolic process; nicotinate nucleotide salvage; response to oxidative stress; vitamin metabolic process; water-soluble vitamin metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NAPRT antibody

 Reference Product  PubMed Publications
 NMNAT3 antibody  >1 publications with NAPRT and NMNAT3
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