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GCSAM Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1492564

Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GCSAM, Polyclonal Antibody
Full Product Name
GCSAM Antibody, Biotin conjugated
Product Gene Name
Product Synonym Names
Germinal center-associated signaling and motility protein; GCSAM; GAL; GCET2; Germinal center B-cell-expressed transcript 2 protein; Germinal center-associated lymphoma protein; hGAL
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: GCSAM (MBS1497349)
Biotin Conjugated Antibody: GCSAM (MBS1492564)
Molecular Weight
19,206 Da
OMIM
607792
3D Structure
ModBase 3D Structure for Q8N6F7
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Biotin
Immunogen
Recombinant human Germinal center-associated signaling and motility protein
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GCSAM antibody
ELISA (EIA)

Other Notes

Small volumes of anti-GCSAM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GCSAM purchase

MBS1492564 is an antibody targeting GCSAM. Also known as GCSAM Antibody, Biotin conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GCSAM. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
germinal center-associated signaling and motility protein isoform 3
NCBI Official Synonym Full Names
germinal center-associated, signaling and motility
NCBI Official Symbol
GCSAM
NCBI Official Synonym Symbols
HGAL; GCAT2; GCET2
UniProt Protein Name
Germinal center-associated signaling and motility protein
UniProt Synonym Protein Names
Germinal center B-cell-expressed transcript 2 protein; Germinal center-associated lymphoma protein; hGAL
UniProt Gene Name
GCSAM
UniProt Synonym Gene Names
GAL; GCET2; hGAL
UniProt Entry Name
GCSAM_HUMAN
NCBI Protein Information
germinal center-associated signaling and motility protein

NCBI Summary for GCSAM

This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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UniProt Comments for GCSAM

GCET2: a protein expressed in normal germinal center B cells, immature B and T cells. Induced by IL4. Its expression strongly predicts survival in diffuse large B-cell lymphoma.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: cytoplasm; plasma membrane

Molecular Function: actin binding; myosin II binding; protein binding; protein kinase binding

Biological Process: regulation of B cell receptor signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GCSAM antibody

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