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Osteocalcin (BGLAP) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1492730

Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Osteocalcin (Bglap), Polyclonal Antibody
Full Product Name
Rabbit anti-rat Osteocalcin polyclonal Antibody
Product Gene Name
anti-Bglap antibody
Product Synonym Names
Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein; Bglap2; Bglap
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: Osteocalcin (MBS1492730)
Biotin Conjugated Antibody: Osteocalcin (MBS968884)
Matching Pairs
Unconjugated Antibody: Osteocalcin (MBS1492730)
FITC Conjugated Antibody: Osteocalcin (MBS1491750)
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Molecular Weight
10,927 Da
3D Structure
ModBase 3D Structure for P04640
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant rat Osteocalcin protein(50-99AA)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-Bglap antibody
ELISA (EIA)

Other Notes

Small volumes of anti-Bglap antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Bglap purchase

MBS1492730 is an antibody targeting Bglap. Also known as Rabbit anti-rat Osteocalcin polyclonal Antibody. Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Bglap. It may not necessarily be applicable to this product.

NCBI GI #
11761543
NCBI GeneID
25295
NCBI Accession #
NP_038200.1
UniProt Primary Accession #
P04640
UniProt Related Accession #
P04640
GenBank Nucleotide #
NM_013414.1
NCBI Official Full Name
osteocalcin preproprotein
NCBI Official Synonym Full Names
bone gamma-carboxyglutamate (gla) protein
NCBI Official Symbol
Bglap
NCBI Official Synonym Symbols
Bgp; Bgpr; Bgpra; Bglap2
UniProt Protein Name
Osteocalcin
UniProt Synonym Protein Names
Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
Protein Family
Osteocalcin
UniProt Gene Name
Bglap
UniProt Synonym Gene Names
Bglap2; BGP
UniProt Entry Name
OSTCN_RAT
NCBI Protein Information
osteocalcin

NCBI Summary for Bglap

highly conserved protein associated with mineralized bone matrix; protein is secreted by calcified tissues and is regulated by vitamin D3 [RGD, Feb 2006]

UniProt Comments for Bglap

osteocalcin: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family.

Protein type: Cell development/differentiation; Secreted, signal peptide; Secreted

Cellular Component: cell projection; cytoplasm; dendrite; extracellular region; extracellular space; Golgi apparatus; perikaryon; rough endoplasmic reticulum

Molecular Function: calcium ion binding; structural constituent of bone

Biological Process: aging; biomineral formation; cell aging; odontogenesis; ossification; osteoblast development; osteoblast differentiation; regulation of bone mineralization; response to activity; response to drug; response to estrogen stimulus; response to ethanol; response to glucocorticoid stimulus; response to gravity; response to hydroxyisoflavone; response to inorganic substance; response to mechanical stimulus; response to nutrient levels; response to organic cyclic substance; response to testosterone stimulus; response to vitamin D; response to vitamin K; response to zinc ion
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Research Articles on Bglap

1. In primary adipocytes, both carboxylated and uncarboxylated osteocalcin increased basal and insulin-stimulated glucose transport.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Bglap antibody

 Reference Product  PubMed Publications
 Runx2 antibody  >57 publications with Bglap and Runx2
 Ibsp antibody  >20 publications with Bglap and Ibsp
 Bmp2 antibody  >14 publications with Bglap and Bmp2
 Bmp4 antibody  >7 publications with Bglap and Bmp4
 Tgfb1 antibody  >3 publications with Bglap and Tgfb1
 Pth antibody  >3 publications with Bglap and Pth
 Atf4 antibody  >2 publications with Bglap and Atf4
 Adipoq antibody  >1 publications with Bglap and Adipoq
 Lep antibody  >1 publications with Bglap and Lep

Pathways associated with anti-Bglap antibody

 Products by Pathway  Pathway Diagram
 Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway antibodies  Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway Diagram
 Gamma-carboxylation Of Protein Precursors Pathway antibodies  Gamma-carboxylation Of Protein Precursors Pathway Diagram
 Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway antibodies  Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Osteoblast Pathway antibodies  Osteoblast Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Removal Of Aminoterminal Propeptides From Gamma-carboxylated Proteins Pathway antibodies  Removal Of Aminoterminal Propeptides From Gamma-carboxylated Proteins Pathway Diagram
 Transport Of Gamma-carboxylated Protein Precursors From The Endoplasmic Reticulum To The Golgi Apparatus Pathway antibodies  Transport Of Gamma-carboxylated Protein Precursors From The Endoplasmic Reticulum To The Golgi Apparatus Pathway Diagram

Diseases associated with anti-Bglap antibody

 Disease Name  Pubmed Publications
 Bone Diseases Antibodies  >13 publications with Bglap and Bone Diseases
 Osteoporosis Antibodies  >11 publications with Bglap and Osteoporosis
 Inflammation Antibodies  >6 publications with Bglap and Inflammation
 Nervous System Diseases Antibodies  >4 publications with Bglap and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >3 publications with Bglap and Cardiovascular Diseases
 Kidney Diseases Antibodies  >3 publications with Bglap and Kidney Diseases
 Insulin Resistance Antibodies  >3 publications with Bglap and Insulin Resistance
 Calcinosis Antibodies  >3 publications with Bglap and Calcinosis
 Necrosis Antibodies  >2 publications with Bglap and Necrosis
 Hypertrophy Antibodies  >2 publications with Bglap and Hypertrophy

Organs/Tissues associated with anti-Bglap antibody

 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >1 publications with Bglap and Mixed
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