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Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1493058

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Peptidyl-prolyl cis-trans isomerase D (PPID), Polyclonal Antibody
Full Product Name
Rabbit anti-human Peptidyl-prolyl cis-trans isomerase D polyclonal Antibody(PPID)
Product Gene Name
anti-PPID antibody
Product Synonym Names
PPIase D; 40 kDa peptidyl-prolyl cis-trans isomerase; Cyclophilin-40; CYP-40; Cyclophilin-related protein; Rotamase D; PPID; CYP40; CYPD
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
40,764 Da
OMIM
601753
3D Structure
ModBase 3D Structure for Q08752
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Peptidyl-prolyl cis-trans isomerase D protein (161-370aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-33066 / sc-33068 / sc-66848
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PPID antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PPID antibody
Recommended dilution: WB:1:500-5000
IHC:1:20-1:200

Western Blot (WB) of anti-PPID antibody

All lanes: Peptidyl-prolyl cis-trans isomerase D antibody at 9ug/ml
Lane 1:mouse brain tissue
Lane 2:A549 whole cell lysate
Lane 3:MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 41kDa
Observed band size: 41kDa
Rabbit Anti-PPID Polyclonal Antibody – Cat# MBS1493058

Immunohistochemistry (IHC) of anti-PPID antibody

Immunohistochemistry of paraffin-embedded human small intestine using MBS1493058 at dilution 1:100
Rabbit Anti-PPID Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1493058

Other Notes

Small volumes of anti-PPID antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPID purchase

MBS1493058 is an antibody targeting PPID. Also known as Rabbit anti-human Peptidyl-prolyl cis-trans isomerase D polyclonal Antibody(PPID). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPID. It may not necessarily be applicable to this product.

NCBI GI #
4826932
NCBI GeneID
5481
NCBI Accession #
NP_005029.1
UniProt Primary Accession #
Q08752
UniProt Secondary Accession #
B2R9V2
UniProt Related Accession #
Q08752
GenBank Nucleotide #
NM_005038.2
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase D
NCBI Official Synonym Full Names
peptidylprolyl isomerase D
NCBI Official Symbol
PPID
NCBI Official Synonym Symbols
CYPD; CYP-40
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase D
UniProt Synonym Protein Names
40 kDa peptidyl-prolyl cis-trans isomerase; Cyclophilin-40; CYP-40; Cyclophilin-related protein; Rotamase D
Protein Family
Peptidyl-prolyl cis-trans isomerase
UniProt Gene Name
PPID
UniProt Synonym Gene Names
CYP40; CYPD; PPIase D; CYP-40
UniProt Entry Name
PPID_HUMAN
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase D

NCBI Summary for PPID

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008]
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UniProt Comments for PPID

PPID: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.

Protein type: Nucleolus; EC 5.2.1.8; Isomerase

Chromosomal Location of Human Ortholog: 4q31.3

Cellular Component: cytoplasm; nucleolus; nucleoplasm; nucleus

Molecular Function: cyclosporin A binding; estrogen receptor binding; heat shock protein binding; Hsp70 protein binding; Hsp90 protein binding; peptidyl-prolyl cis-trans isomerase activity; protein binding; transcription factor binding

Biological Process: apoptosis; negative regulation of transcription from RNA polymerase II promoter; positive regulation of apoptosis; positive regulation of protein secretion; positive regulation of viral genome replication; protein complex assembly; protein folding; protein peptidyl-prolyl isomerization; protein transport; release of virus from host
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Research Articles on PPID

1. Results show that CypD interacts with SPG7 and VDAC to form the mitochondrial permeability transition pore complex (PTP)and its CsA-binding region is necessary for PTP formation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PPID antibody

 Reference Product  PubMed Publications
 STIP1 antibody  >1 publications with PPID and STIP1
 AHSA1 antibody  >1 publications with PPID and AHSA1

Pathways associated with anti-PPID antibody

 Products by Pathway  Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram

Diseases associated with anti-PPID antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >7 publications with PPID and Necrosis
 Disease Models, Animal Antibodies  >6 publications with PPID and Disease Models, Animal
 Hyperplasia Antibodies  >6 publications with PPID and Hyperplasia
 Inflammation Antibodies  >4 publications with PPID and Inflammation
 Cardiovascular Diseases Antibodies  >4 publications with PPID and Cardiovascular Diseases
 Weight Loss Antibodies  >3 publications with PPID and Weight Loss
 Insulin Resistance Antibodies  >3 publications with PPID and Insulin Resistance
 Hemorrhage Antibodies  >3 publications with PPID and Hemorrhage
 Liver Diseases Antibodies  >2 publications with PPID and Liver Diseases
 Fibrosis Antibodies  >2 publications with PPID and Fibrosis

Organs/Tissues associated with anti-PPID antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >41 publications with PPID and Brain
 Blood Antibodies  >40 publications with PPID and Blood
 Heart Antibodies  >5 publications with PPID and Heart
 Liver Antibodies  >4 publications with PPID and Liver
 Prostate Antibodies  >3 publications with PPID and Prostate
 Lung Antibodies  >2 publications with PPID and Lung
 Embryonic Tissue Antibodies  >2 publications with PPID and Embryonic Tissue
 Eye Antibodies  >2 publications with PPID and Eye
 Thyroid Antibodies  >1 publications with PPID and Thyroid
 Pancreas Antibodies  >1 publications with PPID and Pancreas
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