Rabbit Anti-PLEKHA8 Polyclonal Antibody – Cat# MBS1493293

PLEKHA8 Antibody – Rabbit Polyclonal

Name: PLEKHA8 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1493293
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1493293

Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi… More details

$230 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PLEKHA8, Polyclonal Antibody

Full Product Name

PLEKHA8 Antibody, HRP conjugated

Product Gene Name

anti-PLEKHA8 antibody

Product Synonym Names

Pleckstrin homology domain-containing family A member 8; PH domain-containing family A member 8; PLEKHA8; FAPP2; Phosphatidylinositol-four-phosphate adapter protein 2; FAPP-2; Phosphoinositol 4-phosphate adapter protein 2; hFAPP2; Serologically defined breast cancer antigen NY-BR-86

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Purity/Purification

>95%, Protein G Purified

Preparation and Storage

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Matching Pairs

Unconjugated Antibody: PLEKHA8 (MBS7001644)
HRP Conjugated Antibody: PLEKHA8 (MBS1493293)

Molecular Weight

49,462 Da

OMIM

608639

3D Structure

ModBase 3D Structure for Q96JA3

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Conjugate

HRP

Immunogen

Recombinant human Pleckstrin homology domain-containing family A member 8 protein

Santa Cruz Alternative

Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162817

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PLEKHA8 antibody

ELISA (EIA)

Other Notes

Small volumes of anti-PLEKHA8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLEKHA8 purchase

MBS1493293 is an antibody targeting PLEKHA8. Also known as PLEKHA8 Antibody, HRP conjugated. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLEKHA8. It may not necessarily be applicable to this product.

NCBI GI #

308153327

NCBI GeneID

84725

NCBI Accession #

NP_001183955.1

UniProt Primary Accession #

Q96JA3

UniProt Secondary Accession #

Q7Z5V8; Q9BU78; Q9H274; Q9H8Z7; B4DH00

UniProt Related Accession #

Q96JA3

GenBank Nucleotide #

NM_001197026.1

NCBI Official Full Name

pleckstrin homology domain-containing family A member 8 isoform 1

NCBI Official Synonym Full Names

pleckstrin homology domain containing A8

NCBI Official Symbol

PLEKHA8

NCBI Official Synonym Symbols

FAPP2

UniProt Protein Name

Pleckstrin homology domain-containing family A member 8

UniProt Synonym Protein Names

Phosphatidylinositol-four-phosphate adapter protein 2; FAPP-2; Phosphoinositol 4-phosphate adapter protein 2; hFAPP2; Serologically defined breast cancer antigen NY-BR-86

Protein Family

Pleckstrin homology domain-containing family

UniProt Gene Name

PLEKHA8

UniProt Synonym Gene Names

FAPP2; PH domain-containing family A member 8; FAPP-2; Phosphoinositol 4-phosphate adapter protein 2; hFAPP2

UniProt Entry Name

PKHA8_HUMAN

NCBI Protein Information

pleckstrin homology domain-containing family A member 8

UniProt Comments for PLEKHA8

PLEKHA8: Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 7p14.3

Cellular Component: membrane; trans-Golgi network

Molecular Function: glycolipid binding; glycolipid transporter activity

Biological Process: glycolipid transport; lipid transport; protein transport

Research Articles on PLEKHA8

1. Altogether, this study implies that hepatitis C virus coopts FAPP2 for virus genome replication via phosphatidylinositol 4-phosphate binding and glycosphingolipid transport to the hepatitis C virus replication complex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLEKHA8 antibody

Reference Product	PubMed Publications
ARF1 antibody	>1 publications with PLEKHA8 and ARF1

Diseases associated with anti-PLEKHA8 antibody

Disease Name	Pubmed Publications
Chromosome Aberrations Antibodies	>1 publications with PLEKHA8 and Chromosome Aberrations

Organs/Tissues associated with anti-PLEKHA8 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>2 publications with PLEKHA8 and Kidney
Heart Antibodies	>1 publications with PLEKHA8 and Heart
Bone Antibodies	>1 publications with PLEKHA8 and Bone
Brain Antibodies	>1 publications with PLEKHA8 and Brain