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SSR3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1493770

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SSR3, Polyclonal Antibody
Full Product Name
SSR3 Antibody
Product Gene Name
anti-SSR3 antibody
Product Synonym Names
Translocon-associated protein subunit gamma; TRAP-gamma; SSR3; TRAPG; Signal sequence receptor subunit gamma; SSR-gamma
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: SSR3 (MBS1493770)
HRP Conjugated Antibody: SSR3 (MBS1494137)
Matching Pairs
Unconjugated Antibody: SSR3 (MBS1493770)
Biotin Conjugated Antibody: SSR3 (MBS1496346)
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OMIM
606213
3D Structure
ModBase 3D Structure for Q9UNL2
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant Human Translocon-associated protein subunit gamma protein (77-135AA)
Species
Homo sapiens (Human)
Research Area
Epigenetics and Nuclear Signaling
Target Names
SSR3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SSR3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-SSR3 antibody
WB: 1:500-2000
IHC: 1:20-1:200
IF: 1:50-1:200

Western Blot (WB) of anti-SSR3 antibody

Western blot
All lanes: SSR3 antibody at 10ug/ml
Lane 1: Hela whole cell lysate
Lane 2: U87 whole cell lysate
Lane 3: A431 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 22,23 kDa
Observed band size: 21 kDa
Rabbit Anti-SSR3 Polyclonal Antibody – Cat# MBS1493770

Immunohistochemistry (IHC) of anti-SSR3 antibody

Immunohistochemistry of paraffin-embedded human colon cancer using MBS1493770 at dilution of 1:100
Rabbit Anti-SSR3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1493770

Immunohistochemistry (IHC) of anti-SSR3 antibody

Immunohistochemistry of paraffin-embedded human prostate cancer using MBS1493770 at dilution of 1:100
Rabbit Anti-SSR3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1493770

Immunofluorescence (IF) of anti-SSR3 antibody

Immunofluorescent analysis of Hela cells using MBS1493770 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-SSR3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS1493770

Other Notes

Small volumes of anti-SSR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SSR3 purchase

MBS1493770 is an antibody targeting SSR3. Also known as SSR3 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SSR3. It may not necessarily be applicable to this product.

NCBI GI #
815891066
NCBI GeneID
6747
NCBI Accession #
NP_001295126.1
UniProt Primary Accession #
Q9UNL2
UniProt Secondary Accession #
Q549M4; B2R7D0; B4E2P2; D3DNK5
UniProt Related Accession #
Q9UNL2
GenBank Nucleotide #
NM_001308197.1
NCBI Official Full Name
translocon-associated protein subunit gamma isoform 1
NCBI Official Synonym Full Names
signal sequence receptor, gamma (translocon-associated protein gamma)
NCBI Official Symbol
SSR3
NCBI Official Synonym Symbols
TRAPG
UniProt Protein Name
Translocon-associated protein subunit gamma
UniProt Synonym Protein Names
Signal sequence receptor subunit gamma; SSR-gamma
Protein Family
SWI/SNF and RSC complexes
UniProt Gene Name
SSR3
UniProt Synonym Gene Names
TRAPG; TRAP-gamma; SSR-gamma
UniProt Entry Name
SSRG_HUMAN
NCBI Protein Information
translocon-associated protein subunit gamma

NCBI Summary for SSR3

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins/subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non-glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times. [provided by RefSeq, Aug 2010]
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UniProt Comments for SSR3

SSR3: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. Belongs to the TRAP-gamma family.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q25.31

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Biological Process: cellular protein metabolic process; gene expression; SRP-dependent cotranslational protein targeting to membrane; translation
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Research Articles on SSR3

1. translocon-associated protein subunit gamma (TRAPgamma) was identified as a novel TR3 binding partner.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SSR3 antibody

 Reference Product  PubMed Publications
 SSR2 antibody  >3 publications with SSR3 and SSR2
 SSR1 antibody  >1 publications with SSR3 and SSR1
 SSR4 antibody  >1 publications with SSR3 and SSR4

Pathways associated with anti-SSR3 antibody

 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 SRP-dependent Cotranslational Protein Targeting To Membrane Pathway antibodies  SRP-dependent Cotranslational Protein Targeting To Membrane Pathway Diagram
 Translation Pathway antibodies  Translation Pathway Diagram
 Translocon-associated Protein (TRAP) Complex Pathway antibodies  Translocon-associated Protein (TRAP) Complex Pathway Diagram
 Translocon-associated Protein (TRAP) Complex Pathway antibodies  Translocon-associated Protein (TRAP) Complex Pathway Diagram

Diseases associated with anti-SSR3 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with SSR3 and Breast Neoplasms
 Necrosis Antibodies  >1 publications with SSR3 and Necrosis

Organs/Tissues associated with anti-SSR3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with SSR3 and Blood
 Bone Antibodies  >1 publications with SSR3 and Bone
 Stomach Antibodies  >1 publications with SSR3 and Stomach
 Bone Marrow Antibodies  >1 publications with SSR3 and Bone Marrow
 Placenta Antibodies  >1 publications with SSR3 and Placenta
 Lymph Antibodies  >1 publications with SSR3 and Lymph
 Lung Antibodies  >1 publications with SSR3 and Lung
 Vascular Antibodies  >1 publications with SSR3 and Vascular
 Kidney Antibodies  >1 publications with SSR3 and Kidney
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