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SWAP70 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1494308

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SWAP70, Polyclonal Antibody
Full Product Name
SWAP70 Antibody, FITC conjugated
Product Gene Name
anti-SWAP70 antibody
Product Synonym Names
Switch-associated protein 70; SWAP-70; SWAP70; KIAA0640; HSPC321
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: SWAP70 (MBS7004411)
FITC Conjugated Antibody: SWAP70 (MBS1494308)
Molecular Weight
68,998 Da
OMIM
604762
3D Structure
ModBase 3D Structure for Q9UH65
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
FITC
Immunogen
Recombinant human Switch-associated protein 70 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10883 / sc-10882 / sc-130887
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SWAP70 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-SWAP70 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SWAP70 purchase

MBS1494308 is an antibody targeting SWAP70. Also known as SWAP70 Antibody, FITC conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SWAP70. It may not necessarily be applicable to this product.

NCBI GI #
663070936
NCBI GeneID
23075
NCBI Accession #
NP_001284643.1
UniProt Primary Accession #
Q9UH65
UniProt Secondary Accession #
O75135; Q7LCY6; Q9P061; Q9P0Z8; D3DQV1
UniProt Related Accession #
Q9UH65
GenBank Nucleotide #
NM_001297714.1
NCBI Official Full Name
switch-associated protein 70 isoform 2
NCBI Official Synonym Full Names
SWAP switching B-cell complex 70kDa subunit
NCBI Official Symbol
SWAP70
NCBI Official Synonym Symbols
HSPC321; SWAP-70
UniProt Protein Name
Switch-associated protein 70
Protein Family
Switch-associated protein
UniProt Gene Name
SWAP70
UniProt Synonym Gene Names
KIAA0640; SWAP-70
UniProt Entry Name
SWP70_HUMAN
NCBI Protein Information
switch-associated protein 70

UniProt Comments for SWAP70

SWAP-70: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Protein type: GEFs, Rac/Rho; GEFs

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: cytoskeleton; cytosol; lamellipodium; nucleus; plasma membrane

Molecular Function: ATP binding; calcium ion binding; DNA binding; protein binding

Biological Process: actin filament bundle formation; elevation of cytosolic calcium ion concentration; isotype switching; negative regulation of actin filament depolymerization; negative regulation of cell-cell adhesion mediated by integrin; positive regulation of actin filament bundle formation; regulation of protein localization
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Research Articles on SWAP70

1. SWAP70 appears to act as a molecular intermediate between vGPCR and endothelial activation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SWAP70 antibody

 Reference Product  PubMed Publications
 KIT antibody  >1 publications with SWAP70 and KIT
 IRF4 antibody  >1 publications with SWAP70 and IRF4

Diseases associated with anti-SWAP70 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with SWAP70 and Inflammation
 Neurobehavioral Manifestations Antibodies  >1 publications with SWAP70 and Neurobehavioral Manifestations
 Anemia Antibodies  >1 publications with SWAP70 and Anemia
 Brain Diseases Antibodies  >1 publications with SWAP70 and Brain Diseases
 Hyperplasia Antibodies  >1 publications with SWAP70 and Hyperplasia

Organs/Tissues associated with anti-SWAP70 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >25 publications with SWAP70 and Blood
 Bone Antibodies  >12 publications with SWAP70 and Bone
 Bone Marrow Antibodies  >11 publications with SWAP70 and Bone Marrow
 Lymph Node Antibodies  >5 publications with SWAP70 and Lymph Node
 Spleen Antibodies  >5 publications with SWAP70 and Spleen
 Lymph Antibodies  >4 publications with SWAP70 and Lymph
 Vascular Antibodies  >4 publications with SWAP70 and Vascular
 Brain Antibodies  >3 publications with SWAP70 and Brain
 Skin Antibodies  >3 publications with SWAP70 and Skin
 Nerve Antibodies  >2 publications with SWAP70 and Nerve
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