Rabbit IGFBP5 ELISA Kit – Cat# MBS014952

Insulin Like Growth Factor Binding Protein 5 (IGFBP5) ELISA Kit for Rabbit

Name: Rabbit IGFBP5 ELISA Kit; Insulin Like Growth Factor Binding Protein 5; MyBioSource
Brand: MyBioSource
SKU: MBS014952
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS014952

Background: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of IGFBP5 (hereafter termed "analyte") in undiluted… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Insulin Like Growth Factor Binding Protein 5 (IGFBP5), ELISA Kit

Full Product Name

Rabbit Insulin Like Growth Factor Binding Protein 5 ELISA Kit

Product Gene Name

IGFBP5 elisa kit

Species Reactivity

Rabbit

Assay Type

Quantitative Sandwich

Detection Range

15.6ng/ml-500ng/ml

Sensitivity

2.0ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

30,570 Da

Chromosome Location

Chromosome: 2; NC_000002.11 (217536828..217560272, complement). Location: 2q33-q36

OMIM

146734

3D Structure

ModBase 3D Structure for P24593

Other Notes

Small volumes of IGFBP5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGFBP5 purchase

MBS014952 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Insulin Like Growth Factor Binding Protein 5 (IGFBP5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IGFBP5. The ELISA analytical biochemical technique of the MBS014952 kit is based on IGFBP5 antibody-IGFBP5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGFBP5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGFBP5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for IGFBP5. It may not necessarily be applicable to this product.

NCBI GI #

10834982

NCBI GeneID

3488

NCBI Accession #

NP_000590.1

UniProt Primary Accession #

P24593

UniProt Secondary Accession #

Q5U0A3

UniProt Related Accession #

P24593

GenBank Nucleotide #

NM_000599.3

NCBI Official Full Name

insulin-like growth factor-binding protein 5

NCBI Official Synonym Full Names

insulin-like growth factor binding protein 5

NCBI Official Symbol

IGFBP5

NCBI Official Synonym Symbols

IBP5

UniProt Protein Name

Insulin-like growth factor-binding protein 5

Protein Family

Insulin-like growth factor-binding protein

UniProt Gene Name

IGFBP5

UniProt Synonym Gene Names

IBP5; IBP-5; IGF-binding protein 5; IGFBP-5

UniProt Entry Name

IBP5_HUMAN

NCBI Protein Information

insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IGF-binding protein 5

UniProt Comments for IGFBP5

IGFBP5: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Protein type: Secreted; Cell cycle regulation; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: insulin-like growth factor binding protein complex; extracellular space; extracellular region

Molecular Function: protein binding; insulin-like growth factor I binding; fibronectin binding; insulin-like growth factor II binding

Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; mammary gland involution; hair follicle morphogenesis; negative regulation of smooth muscle cell proliferation; negative regulation of insulin-like growth factor receptor signaling pathway; glucose metabolic process; negative regulation of smooth muscle cell migration; glucose homeostasis; signal transduction; osteoblast differentiation; positive regulation of protein kinase B signaling cascade; cellular protein metabolic process; negative regulation of translation; striated muscle cell differentiation; negative regulation of osteoblast differentiation; skeletal muscle growth; regulation of cell growth; negative regulation of cell migration

Research Articles on IGFBP5

1. VEGF may play a regulator role in human ovarian physiology by modulating the expression of IGF-II and IGFBP-5 in luteinized granulosa cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IGFBP5 elisa kit

Reference Product	PubMed Publications
IGF1 elisa kit	>26 publications with IGFBP5 and IGF1
PTH elisa kit	>19 publications with IGFBP5 and PTH
IGF2 elisa kit	>16 publications with IGFBP5 and IGF2
SERPINE1 elisa kit	>7 publications with IGFBP5 and SERPINE1
THBS1 elisa kit	>4 publications with IGFBP5 and THBS1
FHL2 elisa kit	>4 publications with IGFBP5 and FHL2
FN1 elisa kit	>3 publications with IGFBP5 and FN1
PAPPA elisa kit	>3 publications with IGFBP5 and PAPPA

Pathways associated with IGFBP5 elisa kit

Products by Pathway	Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Myometrial Relaxation And Contraction Pathways antibodies	Myometrial Relaxation And Contraction Pathways Diagram
Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies	Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram
Senescence And Autophagy Pathway antibodies	Senescence And Autophagy Pathway Diagram

Diseases associated with IGFBP5 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>156 publications with IGFBP5 and Neoplasms
Carcinoma Antibodies	>50 publications with IGFBP5 and Carcinoma
Breast Neoplasms Antibodies	>47 publications with IGFBP5 and Breast Neoplasms
Nervous System Diseases Antibodies	>34 publications with IGFBP5 and Nervous System Diseases
Necrosis Antibodies	>22 publications with IGFBP5 and Necrosis
Inflammation Antibodies	>21 publications with IGFBP5 and Inflammation
Atrophy Antibodies	>20 publications with IGFBP5 and Atrophy
Cardiovascular Diseases Antibodies	>20 publications with IGFBP5 and Cardiovascular Diseases
Neoplasms, Experimental Antibodies	>19 publications with IGFBP5 and Neoplasms, Experimental
Brain Diseases Antibodies	>19 publications with IGFBP5 and Brain Diseases

Organs/Tissues associated with IGFBP5 elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>142 publications with IGFBP5 and Muscle
Bone Antibodies	>125 publications with IGFBP5 and Bone
Ovary Antibodies	>68 publications with IGFBP5 and Ovary
Connective Tissue Antibodies	>53 publications with IGFBP5 and Connective Tissue
Vascular Antibodies	>50 publications with IGFBP5 and Vascular
Liver Antibodies	>49 publications with IGFBP5 and Liver
Brain Antibodies	>47 publications with IGFBP5 and Brain
Mammary Gland Antibodies	>43 publications with IGFBP5 and Mammary Gland
Kidney Antibodies	>39 publications with IGFBP5 and Kidney
Prostate Antibodies	>38 publications with IGFBP5 and Prostate