• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

UBE2O Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1495286

E2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins (PubMed:23455153, PubMed:24703950). Negatively regulates TRAF6-mediated NF-kappa-B activation independently of its E2… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UBE2O, Polyclonal Antibody
Full Product Name
UBE2O Antibody, HRP conjugated
Product Gene Name
anti-UBE2O antibody
Product Synonym Names
(E3-independent) E2 ubiquitin-conjugating enzyme (EC:2.3.2.242 Publications; UBE2O; KIAA1734; E2/E3 hybrid ubiquitin-protein ligase UBE2O; Ubiquitin carrier protein O; Ubiquitin-conjugating enzyme E2 O; Ubiquitin-conjugating enzyme E2 of 230 kDa; Ubiquitin-conjugating enzyme E2-230K; Ubiquitin-protein ligase O
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: UBE2O (MBS7005326)
HRP Conjugated Antibody: UBE2O (MBS1495286)
Molecular Weight
141,293 Da
3D Structure
ModBase 3D Structure for Q9C0C9
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
HRP
Immunogen
Recombinant human (E3-independent) E2 ubiquitin-conjugating enzyme protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109125
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-UBE2O antibody
ELISA (EIA)

Other Notes

Small volumes of anti-UBE2O antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UBE2O purchase

MBS1495286 is an antibody targeting UBE2O. Also known as UBE2O Antibody, HRP conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for UBE2O. It may not necessarily be applicable to this product.

NCBI GI #
192449449
NCBI GeneID
63893
NCBI Accession #
NP_071349.3
UniProt Primary Accession #
Q9C0C9
UniProt Secondary Accession #
Q69YP4; Q6PIZ2; Q86UA4; Q8N425; Q8TBN1; Q9BSW1; Q9H6E6; Q9H7E4; Q9H9B2; A6NDU5
UniProt Related Accession #
Q9C0C9
GenBank Nucleotide #
NM_022066.3
NCBI Official Full Name
(E3-independent) E2 ubiquitin-conjugating enzyme
NCBI Official Synonym Full Names
ubiquitin conjugating enzyme E2O
NCBI Official Symbol
UBE2O
NCBI Official Synonym Symbols
E2-230K
UniProt Protein Name
(E3-independent) E2 ubiquitin-conjugating enzyme
UniProt Synonym Protein Names
E2/E3 hybrid ubiquitin-protein ligase UBE2O; Ubiquitin carrier protein O; Ubiquitin-conjugating enzyme E2 O; Ubiquitin-conjugating enzyme E2 of 230 kDa; Ubiquitin-conjugating enzyme E2-230K; Ubiquitin-protein ligase O
Protein Family
(E3-independent) E2 ubiquitin-conjugating enzyme
UniProt Gene Name
UBE2O
UniProt Synonym Gene Names
KIAA1734; Ubiquitin-conjugating enzyme E2-230K
UniProt Entry Name
UBE2O_HUMAN
NCBI Protein Information
(E3-independent) E2 ubiquitin-conjugating enzyme

UniProt Comments for UBE2O

UBE2O: Catalyzes the covalent attachment of ubiquitin to other proteins. Belongs to the ubiquitin-conjugating enzyme family.

Protein type: Ubiquitin ligase; EC 6.3.2.19; Ligase; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: cytoplasm; nucleus

Molecular Function: ATP binding; protein binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity

Biological Process: positive regulation of BMP signaling pathway; protein monoubiquitination; retrograde transport, endosome to Golgi
Show more

Research Articles on UBE2O

1. UBE2O defines an atypical ubiquitin-signaling pathway that coordinates the function of BAP1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UBE2O antibody

 Reference Product  PubMed Publications
 UBC antibody  >2 publications with UBE2O and UBC
 SMAD6 antibody  >1 publications with UBE2O and SMAD6
 BAP1 antibody  >1 publications with UBE2O and BAP1

Pathways associated with anti-UBE2O antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies  Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram

Diseases associated with anti-UBE2O antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with UBE2O and Inflammation
 Necrosis Antibodies  >1 publications with UBE2O and Necrosis

Organs/Tissues associated with anti-UBE2O antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with UBE2O and Bone
 Muscle Antibodies  >1 publications with UBE2O and Muscle
 Heart Antibodies  >1 publications with UBE2O and Heart
 Eye Antibodies  >1 publications with UBE2O and Eye
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000