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Ubiquinone Biosynthesis Protein COQ7 Homolog (COQ7) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1495311

Involved in lifespan determination in ubiquinone-independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator (By similarity). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ubiquinone biosynthesis protein COQ7 homolog, Polyclonal Antibody
Full Product Name
Rabbit anti-human Ubiquinone biosynthesis protein COQ7 homolog polyclonal Antibody(COQ7)
Product Gene Name
anti-COQ7 antibody
Product Synonym Names
Coenzyme Q biosynthesis protein 7 homolog; Timing protein clk-1 homolog; COQ7
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
20,158 Da
OMIM
601683
3D Structure
ModBase 3D Structure for Q99807
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Ubiquinone biosynthesis protein COQ7 homolog protein (37-217aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-66353 / sc-66354 / sc-66355 / sc-66356
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-COQ7 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-COQ7 antibody
Recommended dilution: WB:1:200-1000
IHC:1:20-1:200

Western Blot (WB) of anti-COQ7 antibody

All lanes: Ubiquinone biosynthesis protein COQ7 homolog antibody at 6ug/ml+rat heart tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 25,21 kDa
Observed band size: 24 kDa
Rabbit Anti-COQ7 Polyclonal Antibody – Cat# MBS1495311

Immunohistochemistry (IHC) of anti-COQ7 antibody

Immunohistochemistry of paraffin-embedded human breast cancer using MBS1495311 at dilution 1:100
Rabbit Anti-COQ7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1495311

Immunohistochemistry (IHC) of anti-COQ7 antibody

Immunohistochemistry of paraffin-embedded human skeletal muscle using MBS1495311 at dilution 1:100
Rabbit Anti-COQ7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1495311

Other Notes

Small volumes of anti-COQ7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COQ7 purchase

MBS1495311 is an antibody targeting COQ7. Also known as Rabbit anti-human Ubiquinone biosynthesis protein COQ7 homolog polyclonal Antibody(COQ7). Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for COQ7. It may not necessarily be applicable to this product.

NCBI GI #
300244542
NCBI GeneID
10229
NCBI Accession #
NP_001177912.1
UniProt Primary Accession #
Q99807
UniProt Secondary Accession #
Q9BTT7; Q9H0T5; Q9UEW5; Q9UNR5; B2RDA9
UniProt Related Accession #
Q99807
GenBank Nucleotide #
NM_001190983.1
NCBI Official Full Name
5-demethoxyubiquinone hydroxylase, mitochondrial isoform 2
NCBI Official Synonym Full Names
coenzyme Q7 homolog, ubiquinone (yeast)
NCBI Official Symbol
COQ7
NCBI Official Synonym Symbols
CAT5; CLK1; CLK-1
UniProt Protein Name
5-demethoxyubiquinone hydroxylase, mitochondrial
UniProt Synonym Protein Names
Timing protein clk-1 homolog
Protein Family
2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase
UniProt Gene Name
COQ7
UniProt Synonym Gene Names
DMQ hydroxylase
UniProt Entry Name
COQ7_HUMAN
NCBI Protein Information
5-demethoxyubiquinone hydroxylase, mitochondrial

NCBI Summary for COQ7

The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
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UniProt Comments for COQ7

COQ7: Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator. Belongs to the COQ7 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - ubiquinone and other terpenoid-quinone biosynthesis; Mitochondrial

Chromosomal Location of Human Ortholog: 16p12.3

Cellular Component: mitochondrial inner membrane; mitochondrion; nucleus

Molecular Function: chromatin binding; metal ion binding; monooxygenase activity; protein binding

Biological Process: age-dependent response to oxidative stress; determination of adult life span; in utero embryonic development; negative regulation of transcription from RNA polymerase II promoter; neural tube formation; neurogenesis; organelle ATP synthesis coupled electron transport; positive regulation of transcription from RNA polymerase II promoter; response to drug; ubiquinone biosynthetic process
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Research Articles on COQ7

1. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-COQ7 antibody

 Reference Product  PubMed Publications
 COQ9 antibody  >23 publications with COQ7 and COQ9
 COQ6 antibody  >13 publications with COQ7 and COQ6
 COQ4 antibody  >9 publications with COQ7 and COQ4
 COQ3 antibody  >9 publications with COQ7 and COQ3
 COQ2 antibody  >4 publications with COQ7 and COQ2
 COQ5 antibody  >4 publications with COQ7 and COQ5
 ADCK3 antibody  >1 publications with COQ7 and ADCK3
 ADCK4 antibody  >1 publications with COQ7 and ADCK4

Pathways associated with anti-COQ7 antibody

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Ubiquinol Biosynthesis Pathway antibodies  Ubiquinol Biosynthesis Pathway Diagram
 Ubiquinone And Other Terpenoid-quinone Biosynthesis Pathway antibodies  Ubiquinone And Other Terpenoid-quinone Biosynthesis Pathway Diagram
 Ubiquinone And Other Terpenoid-quinone Biosynthesis Pathway antibodies  Ubiquinone And Other Terpenoid-quinone Biosynthesis Pathway Diagram
 Ubiquinone Biosynthesis, Eukaryotes, 4-hydroxybenzoate => Ubiquinone Pathway antibodies  Ubiquinone Biosynthesis, Eukaryotes, 4-hydroxybenzoate => Ubiquinone Pathway Diagram
 Ubiquinone Biosynthesis, Eukaryotes, 4-hydroxybenzoate => Ubiquinone Pathway antibodies  Ubiquinone Biosynthesis, Eukaryotes, 4-hydroxybenzoate => Ubiquinone Pathway Diagram

Diseases associated with anti-COQ7 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >5 publications with COQ7 and Cardiovascular Diseases
 Heart Diseases Antibodies  >3 publications with COQ7 and Heart Diseases
 Inflammation Antibodies  >2 publications with COQ7 and Inflammation
 Death Antibodies  >2 publications with COQ7 and Death
 Carcinoma Antibodies  >1 publications with COQ7 and Carcinoma
 Immune System Diseases Antibodies  >1 publications with COQ7 and Immune System Diseases
 Kidney Diseases Antibodies  >1 publications with COQ7 and Kidney Diseases
 Hypertrophy Antibodies  >1 publications with COQ7 and Hypertrophy
 Dyslipidemias Antibodies  >1 publications with COQ7 and Dyslipidemias
 Liver Diseases Antibodies  >1 publications with COQ7 and Liver Diseases

Organs/Tissues associated with anti-COQ7 antibody

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >9 publications with COQ7 and Heart
 Kidney Antibodies  >4 publications with COQ7 and Kidney
 Brain Antibodies  >3 publications with COQ7 and Brain
 Vascular Antibodies  >2 publications with COQ7 and Vascular
 Lung Antibodies  >2 publications with COQ7 and Lung
 Embryonic Tissue Antibodies  >2 publications with COQ7 and Embryonic Tissue
 Ganglia Antibodies  >1 publications with COQ7 and Ganglia
 Eye Antibodies  >1 publications with COQ7 and Eye
 Testis Antibodies  >1 publications with COQ7 and Testis
 Intestine Antibodies  >1 publications with COQ7 and Intestine
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