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GOSR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1495384

Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role… More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GOSR1, Polyclonal Antibody
Full Product Name
GOSR1 Antibody
Product Gene Name
anti-GOSR1 antibody
Product Synonym Names
28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28; GOSR1; GS28
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
21,214 Da
OMIM
604026
3D Structure
ModBase 3D Structure for O95249
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Golgi SNAP receptor complex member 1 protein (1-115aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-15270 / sc-15271 / sc-30096
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GOSR1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-GOSR1 antibody
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200

Western Blot (WB) of anti-GOSR1 antibody

Western blot
All lanes: GOSR1 antibody at 16ug/ml+mouse liver tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 29,22 kDa
Observed band size: 29 kDa
Rabbit Anti-GOSR1 Polyclonal Antibody – Cat# MBS1495384

Immunohistochemistry (IHC) of anti-GOSR1 antibody

Immunohistochemistry of paraffin-embedded human colon cancer using MBS1495384 at dilution 1:100
Rabbit Anti-GOSR1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1495384

Immunohistochemistry (IHC) of anti-GOSR1 antibody

Immunohistochemistry of paraffin-embedded human placenta tissue using MBS1495384 at dilution 1:100
Rabbit Anti-GOSR1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1495384

Other Notes

Small volumes of anti-GOSR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GOSR1 purchase

MBS1495384 is an antibody targeting GOSR1. Also known as GOSR1 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GOSR1. It may not necessarily be applicable to this product.

NCBI GI #
55770856
NCBI GeneID
9527
NCBI Accession #
NP_001007025.1
UniProt Primary Accession #
O95249
UniProt Secondary Accession #
O75392; J3KST5
UniProt Related Accession #
O95249
GenBank Nucleotide #
NM_001007024.1
NCBI Official Full Name
Golgi SNAP receptor complex member 1 isoform 3
NCBI Official Synonym Full Names
golgi SNAP receptor complex member 1
NCBI Official Symbol
GOSR1
NCBI Official Synonym Symbols
P28; GS28; GOS28; GOLIM2; GOS-28; GOS28/P28
UniProt Protein Name
Golgi SNAP receptor complex member 1
UniProt Synonym Protein Names
28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28
Protein Family
Golgi SNAP receptor complex
UniProt Gene Name
GOSR1
UniProt Synonym Gene Names
GS28; GOS-28
UniProt Entry Name
GOSR1_HUMAN
NCBI Protein Information
Golgi SNAP receptor complex member 1

NCBI Summary for GOSR1

This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for GOSR1

GOSR1: a single-pass type IV Golgi membrane protein. Enriched on vesicular components at the terminal rims of the Golgi. Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. Identified in a unique SNARE complex composed of the Golgi SNAREs GOSR2, STX5, GABARAPL2 and YKT6.

Protein type: Membrane protein, integral; Vesicle; Autophagy

Chromosomal Location of Human Ortholog: 17q11

Cellular Component: cis-Golgi network; Golgi apparatus; Golgi medial cisterna; Golgi membrane; integral to membrane; membrane; SNARE complex

Molecular Function: SNAP receptor activity; SNARE binding

Biological Process: cellular protein metabolic process; ER to Golgi vesicle-mediated transport; intra-Golgi vesicle-mediated transport; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine; protein transport; regulation of vesicle targeting, to, from or within Golgi; retrograde transport, endosome to Golgi; vesicle fusion
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Research Articles on GOSR1

1. Golgi vesicles, presumably with COPI, serve to inhibit intra-Golgi transport by the extraction of GS27 and GS28 from the Golgi cisternae, which blocks the formation of inter-cisternal connections

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GOSR1 antibody

 Reference Product  PubMed Publications
 GOSR2 antibody  >5 publications with GOSR1 and GOSR2
 BET1L antibody  >5 publications with GOSR1 and BET1L
 YKT6 antibody  >5 publications with GOSR1 and YKT6
 GABARAPL2 antibody  >2 publications with GOSR1 and GABARAPL2

Pathways associated with anti-GOSR1 antibody

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 COPI-mediated Anterograde Transport Pathway antibodies  COPI-mediated Anterograde Transport Pathway Diagram
 ER To Golgi Anterograde Transport Pathway antibodies  ER To Golgi Anterograde Transport Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 Transport To The Golgi And Subsequent Modification Pathway antibodies  Transport To The Golgi And Subsequent Modification Pathway Diagram
 Vesicle-mediated Transport Pathway antibodies  Vesicle-mediated Transport Pathway Diagram

Diseases associated with anti-GOSR1 antibody

 Disease Name  Pubmed Publications
 Hypertension Antibodies  >1 publications with GOSR1 and Hypertension
 Abnormalities, Multiple Antibodies  >1 publications with GOSR1 and Abnormalities, Multiple
 Abnormalities, Drug-Induced Antibodies  >1 publications with GOSR1 and Abnormalities, Drug-Induced
 Carcinoma, Hepatocellular Antibodies  >1 publications with GOSR1 and Carcinoma, Hepatocellular
 Heart Diseases Antibodies  >1 publications with GOSR1 and Heart Diseases
 Hypertrophy Antibodies  >1 publications with GOSR1 and Hypertrophy

Organs/Tissues associated with anti-GOSR1 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >4 publications with GOSR1 and Nerve
 Kidney Antibodies  >4 publications with GOSR1 and Kidney
 Lung Antibodies  >2 publications with GOSR1 and Lung
 Brain Antibodies  >2 publications with GOSR1 and Brain
 Heart Antibodies  >1 publications with GOSR1 and Heart
 Blood Antibodies  >1 publications with GOSR1 and Blood
 Liver Antibodies  >1 publications with GOSR1 and Liver
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