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KLHL22 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1496077

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KLHL22, Polyclonal Antibody
Full Product Name
KLHL22 Antibody
Product Gene Name
Product Synonym Names
Kelch-like protein 22; KLHL22
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: KLHL22 (MBS1496077)
Biotin Conjugated Antibody: KLHL22 (MBS1493782)
Matching Pairs
Unconjugated Antibody: KLHL22 (MBS1496077)
FITC Conjugated Antibody: KLHL22 (MBS1494057)
Molecular Weight
55,567 Da
3D Structure
ModBase 3D Structure for Q53GT1
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Kelch-like protein 22 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-86509 / sc-86510
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KLHL22 antibody
ELISA (EIA), Western Blot (WB)

Western Blot (WB) of anti-KLHL22 antibody

Western blot
All lanes: KLHL22 antibody at 8ug/ml
Lane 1: Jurkat whole cell lysate
Lane 2: NIH/3T3 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 72,56 kDa
Observed band size: 72 kDa
Rabbit Anti-KLHL22 Polyclonal Antibody – Cat# MBS1496077

Other Notes

Small volumes of anti-KLHL22 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLHL22 purchase

MBS1496077 is an antibody targeting KLHL22. Also known as KLHL22 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KLHL22. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
kelch-like protein 22
NCBI Official Synonym Full Names
kelch like family member 22
NCBI Official Symbol
KLHL22
NCBI Official Synonym Symbols
KELCHL
UniProt Protein Name
Kelch-like protein 22
Protein Family
UniProt Gene Name
KLHL22
UniProt Entry Name
KLH22_HUMAN
NCBI Protein Information
kelch-like protein 22

UniProt Comments for KLHL22

KLHL22: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for cell division. BCR E3 ubiquitin ligase complexes mediate the ubiquitination of target proteins.

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: centrosome; cytoplasm; polar microtubule

Molecular Function: protein binding; ubiquitin-protein ligase activity

Biological Process: cell division; mitotic cell cycle spindle assembly checkpoint; mitotic sister chromatid segregation; protein monoubiquitination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-KLHL22 antibody

Organs/Tissues associated with anti-KLHL22 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with KLHL22 and Liver
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