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Eukaryotic Translation Initiation Factor 4e-Binding Protein 3 (EIF4EBP3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1496537

Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast,… More details

$230 / 0.05 mg +1 FREE 8GB USB
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Eukaryotic translation initiation factor 4E-binding protein 3 (EIF4EBP3), Polyclonal Antibody
Full Product Name
Rabbit anti-human Eukaryotic translation initiation factor 4E-binding protein 3 polyclonal Antibody(EIF4EBP3), FITC
Product Gene Name
Product Synonym Names
4E-BP3; eIF4E-binding protein 3; EIF4EBP3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: EIF4EBP3 (MBS1497415)
FITC Conjugated Antibody: EIF4EBP3 (MBS1496537)
Molecular Weight
10,873 Da
OMIM
603483
3D Structure
ModBase 3D Structure for O60516
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
FITC
Immunogen
Recombinant human Eukaryotic translation initiation factor 4E-binding protein 3 protein(1-100AA)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162463 / sc-162464
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-EIF4EBP3 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-EIF4EBP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EIF4EBP3 purchase

MBS1496537 is an antibody targeting EIF4EBP3. Also known as Rabbit anti-human Eukaryotic translation initiation factor 4E-binding protein 3 polyclonal Antibody(EIF4EBP3), FITC. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF4EBP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
eukaryotic translation initiation factor 4E-binding protein 3
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 4E binding protein 3
NCBI Official Symbol
EIF4EBP3
NCBI Official Synonym Symbols
4EBP3; 4E-BP3
UniProt Protein Name
Eukaryotic translation initiation factor 4E-binding protein 3
UniProt Gene Name
EIF4EBP3
UniProt Synonym Gene Names
4E-BP3; eIF4E-binding protein 3
UniProt Entry Name
4EBP3_HUMAN
NCBI Protein Information
eukaryotic translation initiation factor 4E-binding protein 3

NCBI Summary for EIF4EBP3

This gene encodes a member of the EIF4EBP family, which consists of proteins that bind to eukaryotic translation initiation factor 4E and regulate its assembly into EIF4F, the multi-subunit translation initiation factor that recognizes the mRNA cap structure. Read-through transcription from the neighboring upstream gene (MASK or ANKHD1) generates a transcript (MASK-BP3) that encodes a protein comprised of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Oct 2010]
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UniProt Comments for EIF4EBP3

4E-BP3: Regulates eIF4E activity by preventing its assembly into the eIF4F complex. EIF4EBP3 interacts with EIF4E. Expression is highest in skeletal muscle, heart, kidney, and pancreas, whereas there is very little expression in brain and thymus. Belongs to the eIF4E-binding protein family.

Protein type: Translation initiation; Translation

Chromosomal Location of Human Ortholog: 5q31.3

Cellular Component: cytoplasm; eukaryotic translation initiation factor 4F complex; membrane

Molecular Function: eukaryotic initiation factor 4E binding; protein binding; translation repressor activity

Biological Process: negative regulation of translational initiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EIF4EBP3 antibody

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