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Beta-Catenin-Interacting Protein 1 (CTNNBIP1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1496924

Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Beta-catenin-interacting protein 1 (CTNNBIP1), Polyclonal Antibody
Full Product Name
Rabbit anti-human Beta-catenin-interacting protein 1 polyclonal Antibody(CTNNBIP1)
Product Gene Name
anti-CTNNBIP1 antibody
Product Synonym Names
Inhibitor of beta-catenin and Tcf-4; CTNNBIP1; ICAT
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
9,170 Da
OMIM
607758
3D Structure
ModBase 3D Structure for Q9NSA3
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Beta-catenin-interacting protein 1 protein(1-81aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-25176 / sc-33964 / sc-25175
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CTNNBIP1 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-CTNNBIP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CTNNBIP1 purchase

MBS1496924 is an antibody targeting CTNNBIP1. Also known as Rabbit anti-human Beta-catenin-interacting protein 1 polyclonal Antibody(CTNNBIP1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CTNNBIP1. It may not necessarily be applicable to this product.

NCBI GI #
59889555
NCBI GeneID
56998
NCBI Accession #
NP_001012329.1
UniProt Primary Accession #
Q9NSA3
UniProt Secondary Accession #
Q5T4V2
UniProt Related Accession #
Q9NSA3
GenBank Nucleotide #
NM_001012329.1
NCBI Official Full Name
beta-catenin-interacting protein 1
NCBI Official Synonym Full Names
catenin beta interacting protein 1
NCBI Official Symbol
CTNNBIP1
NCBI Official Synonym Symbols
ICAT
UniProt Protein Name
Beta-catenin-interacting protein 1
UniProt Synonym Protein Names
Inhibitor of beta-catenin and Tcf-4
Protein Family
Beta-catenin-interacting protein
UniProt Gene Name
CTNNBIP1
UniProt Synonym Gene Names
ICAT
UniProt Entry Name
CNBP1_HUMAN
NCBI Protein Information
beta-catenin-interacting protein 1

NCBI Summary for CTNNBIP1

The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for CTNNBIP1

CTNNBIP1: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. Belongs to the CTNNBIP1 family.

Protein type: Cell development/differentiation; Inhibitor

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: beta-catenin destruction complex; cytoplasm; cytosol; nucleoplasm; nucleus

Molecular Function: beta-catenin binding; protein binding

Biological Process: anterior/posterior pattern formation; negative regulation of DNA binding; negative regulation of protein binding; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; negative regulation of Wnt receptor signaling pathway; positive regulation of monocyte differentiation; positive regulation of osteoblast differentiation; regulation of vascular permeability during acute inflammatory response; ureteric bud branching; Wnt receptor signaling pathway
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Research Articles on CTNNBIP1

1. Finally, pro-incubation with idebenone inhibited mitochondrial dysfunction induced by oxLDL through the mitochondrial-dependent apoptotic pathway and GSK3beta/beta-catenin signalling pathways.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CTNNBIP1 antibody

 Reference Product  PubMed Publications
 CTNNB1 antibody  >38 publications with CTNNBIP1 and CTNNB1
 APC antibody  >7 publications with CTNNBIP1 and APC
 TCF7L2 antibody  >2 publications with CTNNBIP1 and TCF7L2

Pathways associated with anti-CTNNBIP1 antibody

 Products by Pathway  Pathway Diagram
 Deactivation Of The Beta-catenin Transactivating Complex Pathway antibodies  Deactivation Of The Beta-catenin Transactivating Complex Pathway Diagram
 Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies  Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Wnt Pathway antibodies  Signaling By Wnt Pathway Diagram
 TCF Dependent Signaling In Response To WNT Pathway antibodies  TCF Dependent Signaling In Response To WNT Pathway Diagram
 Wnt Signaling Pathway NetPath antibodies  Wnt Signaling Pathway NetPath Diagram
 Wnt Signaling Pathway antibodies  Wnt Signaling Pathway Diagram
 Wnt Signaling Pathway antibodies  Wnt Signaling Pathway Diagram

Diseases associated with anti-CTNNBIP1 antibody

 Disease Name  Pubmed Publications
 Liver Neoplasms Antibodies  >4 publications with CTNNBIP1 and Liver Neoplasms
 Liver Diseases Antibodies  >3 publications with CTNNBIP1 and Liver Diseases
 Kidney Diseases Antibodies  >2 publications with CTNNBIP1 and Kidney Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with CTNNBIP1 and Carcinoma, Hepatocellular
 Cell Transformation, Neoplastic Antibodies  >2 publications with CTNNBIP1 and Cell Transformation, Neoplastic
 Chromosome Aberrations Antibodies  >2 publications with CTNNBIP1 and Chromosome Aberrations
 Lung Neoplasms Antibodies  >1 publications with CTNNBIP1 and Lung Neoplasms
 Hepatomegaly Antibodies  >1 publications with CTNNBIP1 and Hepatomegaly
 Disease Models, Animal Antibodies  >1 publications with CTNNBIP1 and Disease Models, Animal
 Fibrosis Antibodies  >1 publications with CTNNBIP1 and Fibrosis

Organs/Tissues associated with anti-CTNNBIP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with CTNNBIP1 and Blood
 Kidney Antibodies  >6 publications with CTNNBIP1 and Kidney
 Embryonic Tissue Antibodies  >5 publications with CTNNBIP1 and Embryonic Tissue
 Liver Antibodies  >5 publications with CTNNBIP1 and Liver
 Brain Antibodies  >4 publications with CTNNBIP1 and Brain
 Eye Antibodies  >3 publications with CTNNBIP1 and Eye
 Connective Tissue Antibodies  >3 publications with CTNNBIP1 and Connective Tissue
 Bone Antibodies  >3 publications with CTNNBIP1 and Bone
 Vascular Antibodies  >2 publications with CTNNBIP1 and Vascular
 Lung Antibodies  >2 publications with CTNNBIP1 and Lung
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