Rabbit Anti-KLHL42 Polyclonal Antibody – Cat# MBS1497232

KLHL42 Antibody – Rabbit Polyclonal

Name: KLHL42 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1497232
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1497232

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in… More details

$230 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KLHL42, Polyclonal Antibody

Full Product Name

KLHL42 Antibody, Biotin conjugated

Product Gene Name

anti-KLHL42 antibody

Product Synonym Names

Kelch-like protein 42; KLHL42; KIAA1340; KLHDC5; Cullin-3-binding protein 9; Ctb9; Kelch domain-containing protein 5

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

>95%, Protein G Purified

Preparation and Storage

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Matching Pairs

Unconjugated Antibody: KLHL42 (MBS1494382)
Biotin Conjugated Antibody: KLHL42 (MBS1497232)

Molecular Weight

56,868 Da

3D Structure

ModBase 3D Structure for Q9P2K6

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Conjugate

Biotin

Immunogen

Recombinant human Kelch-like protein 42 protein

Santa Cruz Alternative

Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-168370 / sc-168371

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-KLHL42 antibody

ELISA (EIA)

Other Notes

Small volumes of anti-KLHL42 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLHL42 purchase

MBS1497232 is an antibody targeting KLHL42. Also known as KLHL42 Antibody, Biotin conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KLHL42. It may not necessarily be applicable to this product.

NCBI GI #

55749726

NCBI GeneID

57542

NCBI Accession #

NP_065833.1

UniProt Primary Accession #

Q9P2K6

UniProt Secondary Accession #

Q2VPK1; Q8N334

UniProt Related Accession #

Q9P2K6

GenBank Nucleotide #

NM_020782.1

NCBI Official Full Name

kelch-like protein 42

NCBI Official Synonym Full Names

kelch like family member 42

NCBI Official Symbol

KLHL42

NCBI Official Synonym Symbols

Ctb9; KLHDC5

UniProt Protein Name

Kelch-like protein 42

UniProt Synonym Protein Names

Cullin-3-binding protein 9; Ctb9; Kelch domain-containing protein 5

Protein Family

Kelch-like protein

UniProt Gene Name

KLHL42

UniProt Synonym Gene Names

KIAA1340; KLHDC5; Ctb9

UniProt Entry Name

KLH42_HUMAN

NCBI Protein Information

kelch-like protein 42

UniProt Comments for KLHL42

KLHDC5: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis. Up-regulated during mitosis. Component of the BCR(KLHL42) E3 ubiquitin ligase complex, at least composed of CUL3 and KLHL42. Interacts (via the BTB domain) with CUL3. Interacts (via the kelch domains) with KATNA1

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 12p11.22

Cellular Component: cytoplasm; spindle

Molecular Function: protein binding; ubiquitin-protein ligase activity

Biological Process: cell division; mitosis; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of microtubule-based process

Research Articles on KLHL42

1. Cul3-deficient cells or Ctb9/KLHDC5-deficient cells show an increase in p60/katanin levels, indicating that Cul3/Ctb9/KLHDC5 is required for efficient p60/katanin removal

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.