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GPS1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1497317

Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPS1, Polyclonal Antibody
Full Product Name
GPS1 Antibody
Product Gene Name
Product Synonym Names
SGN1; Signalosome subunit 1; G protein pathway suppressor 1; GPS-1; JAB1-containing signalosome subunit 1; Protein MFH; GPS1; COPS1; CSN1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
59,050 Da
OMIM
601934
3D Structure
ModBase 3D Structure for Q13098
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human COP9 signalosome complex subunit 1 protein (222-491aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47853 / sc-47854 / sc-47856 / sc-47855 / sc-292637
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GPS1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-GPS1 antibody
Recommended dilution: IHC:1:20-1:200

Immunohistochemistry (IHC) of anti-GPS1 antibody

Immunohistochemistry of paraffin-embedded human breast cancer using MBS1497317 at dilution 1:100
Rabbit Anti-GPS1 Polyclonal Antibody – Cat# MBS1497317

Immunohistochemistry (IHC) of anti-GPS1 antibody

Immunohistochemistry of paraffin-embedded human adrenal gland using MBS1497317 at dilution 1:100
Rabbit Anti-GPS1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1497317

Other Notes

Small volumes of anti-GPS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPS1 purchase

MBS1497317 is an antibody targeting GPS1. Also known as GPS1 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GPS1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
COP9 signalosome complex subunit 1 isoform 2
NCBI Official Synonym Full Names
G protein pathway suppressor 1
NCBI Official Symbol
GPS1
NCBI Official Synonym Symbols
CSN1; COPS1
UniProt Protein Name
COP9 signalosome complex subunit 1
UniProt Synonym Protein Names
G protein pathway suppressor 1; GPS-1; JAB1-containing signalosome subunit 1; Protein MFH
UniProt Gene Name
GPS1
UniProt Synonym Gene Names
COPS1; CSN1; SGN1; Signalosome subunit 1; GPS-1
UniProt Entry Name
CSN1_HUMAN
NCBI Protein Information
COP9 signalosome complex subunit 1

NCBI Summary for GPS1

This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for GPS1

COPS1: a protein that suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. Shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: cytoplasm; nucleoplasm; signalosome

Molecular Function: GTPase inhibitor activity; protein binding

Biological Process: cell cycle; cullin deneddylation; DNA repair; inactivation of MAPK activity; JNK cascade; nucleotide-excision repair; nucleotide-excision repair, DNA damage recognition; transcription-coupled nucleotide-excision repair
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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