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Glandular Kallikrein-7 (KLK7) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1497383

Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Predominant kallikrein protein in the kidney. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glandular kallikrein-7 (Klk7), Polyclonal Antibody
Full Product Name
Rabbit anti-rat Glandular kallikrein-7, submandibular/renal polyclonal Antibody, FITC
Product Gene Name
anti-Klk7 antibody
Product Synonym Names
rGK-7; Esterase B; Kallikrein-related protein K1; Proteinase A; RSKG-7; Tissue kallikrein; Klk-7
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: Klk7 (MBS1493226)
FITC Conjugated Antibody: Klk7 (MBS1497383)
Molecular Weight
28,972 Da
3D Structure
ModBase 3D Structure for P36373
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
FITC
Immunogen
Recombinant rat Glandular kallikrein-7, submandibular/renal protein(25-261AA)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-Klk7 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-Klk7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Klk7 purchase

MBS1497383 is an antibody targeting Klk7. Also known as Rabbit anti-rat Glandular kallikrein-7, submandibular/renal polyclonal Antibody, FITC. Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Klk7. It may not necessarily be applicable to this product.

NCBI GI #
6981132
NCBI GeneID
24523
NCBI Accession #
NP_036725.1
UniProt Primary Accession #
P36373
UniProt Related Accession #
P36373
GenBank Nucleotide #
NM_012593.1
NCBI Official Full Name
kallikrein 1
NCBI Official Synonym Full Names
kallikrein 1
NCBI Official Symbol
Klk1
NCBI Official Synonym Symbols
Kal; KALA; Klk5; Klk7; Klk1l; RGK-7; Klk1c7; RSKG-7; RATKALA
UniProt Protein Name
Glandular kallikrein-7, submandibular/renal
UniProt Synonym Protein Names
Esterase B; Kallikrein-related protein K1; Proteinase A; RSKG-7; Tissue kallikrein
Protein Family
Glandular kallikrein
UniProt Gene Name
Klk7
UniProt Synonym Gene Names
Klk-7; rGK-7
UniProt Entry Name
KLK7_RAT
NCBI Protein Information
kallikrein 1

NCBI Summary for Klk7

serine protease; involved in processing of bioactive peptides [RGD, Feb 2006]

UniProt Comments for Klk7

KLK7: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.21.35; Secreted, signal peptide; Secreted; Protease

Cellular Component: acrosome; apical part of cell; nucleus

Molecular Function: endopeptidase activity; serine-type endopeptidase activity

Biological Process: positive regulation of acute inflammatory response; positive regulation of apoptosis; positive regulation of cell proliferation; proteolysis; response to nutrient
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Research Articles on Klk7

1. Gonadectomy influences blood pressure through the kallikrein-kinin system.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Klk7 antibody

 Reference Product  PubMed Publications
 Set antibody  >2 publications with Klk7 and Set

Pathways associated with anti-Klk7 antibody

 Products by Pathway  Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram

Diseases associated with anti-Klk7 antibody

 Disease Name  Pubmed Publications
 Vascular Diseases Antibodies  >20 publications with Klk7 and Vascular Diseases
 Kidney Diseases Antibodies  >17 publications with Klk7 and Kidney Diseases
 Hypertension Antibodies  >16 publications with Klk7 and Hypertension
 Inflammation Antibodies  >10 publications with Klk7 and Inflammation
 Lung Diseases Antibodies  >8 publications with Klk7 and Lung Diseases
 Heart Diseases Antibodies  >6 publications with Klk7 and Heart Diseases
 Disease Models, Animal Antibodies  >5 publications with Klk7 and Disease Models, Animal
 Fibrosis Antibodies  >5 publications with Klk7 and Fibrosis
 Renal Insufficiency Antibodies  >4 publications with Klk7 and Renal Insufficiency
 Hypertrophy Antibodies  >3 publications with Klk7 and Hypertrophy

Organs/Tissues associated with anti-Klk7 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >25 publications with Klk7 and Kidney
 Salivary Gland Antibodies  >6 publications with Klk7 and Salivary Gland
 Eye Antibodies  >1 publications with Klk7 and Eye
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