Rabbit Anti-DCN1 Polyclonal Antibody – Cat# MBS1497790

Immunohistochemistry of paraffin-embedded human kidney using MBS1497790 at dilution 1:100

Like Protein 1 (DCN1) Antibody – Rabbit Polyclonal

Name: DCN1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1497790
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1497790

Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin… More details

$230 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DCN1-like protein 1, Polyclonal Antibody

Full Product Name

Rabbit anti-human DCN1-like protein 1 polyclonal Antibody

Product Gene Name

anti-DCN1 antibody

Product Synonym Names

DCUN1 domain-containing protein 1; Defective in cullin neddylation protein 1-like protein 1; Squamous cell carcinoma-related oncogene; DCUN1L1; RP42; SCCRO; DCUN1D1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

Caprylic Acid Ammonium Sulfate Precipitation Purified

Preparation and Storage

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Matching Pairs

Unconjugated Antibody: DCN1 (MBS1497790)
FITC Conjugated Antibody: DCN1 (MBS968804)

Matching Pairs

Unconjugated Antibody: DCN1 (MBS1497790)
Biotin Conjugated Antibody: DCN1 (MBS1491817)

Molecular Weight

30,124 Da

OMIM

605905

3D Structure

ModBase 3D Structure for Q96GG9

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Conjugate

Non-conjugated

Immunogen

Recombinant human DCN1-like protein 1 protein(1-259aa)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-DCN1 antibody

ELISA (EIA), Immunohistochemistry (IHC)

Application Notes for anti-DCN1 antibody

Recommended dilution: IHC:1:20-1:200

Other Notes

Small volumes of anti-DCN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DCN1 purchase

MBS1497790 is an antibody targeting DCN1. Also known as Rabbit anti-human DCN1-like protein 1 polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DCN1. It may not necessarily be applicable to this product.

NCBI GI #

809281410

NCBI GeneID

54165

NCBI Accession #

NP_001295030.1

UniProt Primary Accession #

Q96GG9

UniProt Secondary Accession #

Q7L3G9; Q8TEX7; Q9H6M1; Q9HCT3; B2RB37

UniProt Related Accession #

Q96GG9

GenBank Nucleotide #

NM_001308101.1

NCBI Official Full Name

DCN1-like protein 1 isoform 2

NCBI Official Synonym Full Names

defective in cullin neddylation 1 domain containing 1

NCBI Official Symbol

DCUN1D1

NCBI Official Synonym Symbols

RP42; SCRO; Tes3; DCNL1; SCCRO; DCUN1L1

UniProt Protein Name

DCN1-like protein 1

UniProt Synonym Protein Names

DCUN1 domain-containing protein 1; Defective in cullin neddylation protein 1-like protein 1; Squamous cell carcinoma-related oncogene

Protein Family

Defective in cullin neddylation protein

UniProt Gene Name

DCUN1D1

UniProt Synonym Gene Names

DCUN1L1; RP42; SCCRO

UniProt Entry Name

DCNL1_HUMAN

NCBI Protein Information

DCN1-like protein 1

UniProt Comments for DCN1

DCUN1D1: Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression.

Protein type: Ubiquitin conjugating system; Oncoprotein

Chromosomal Location of Human Ortholog: 3q26.3

Cellular Component: nucleus; ubiquitin ligase complex

Molecular Function: protein binding; small conjugating protein binding; ubiquitin conjugating enzyme binding

Biological Process: positive regulation of ubiquitin-protein ligase activity; protein neddylation

Research Articles on DCN1

1. The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DCN1 antibody

Reference Product	PubMed Publications
NEDD8 antibody	>7 publications with DCN1 and NEDD8
RBX1 antibody	>2 publications with DCN1 and RBX1
CUL1 antibody	>2 publications with DCN1 and CUL1
CUL2 antibody	>1 publications with DCN1 and CUL2

Diseases associated with anti-DCN1 antibody

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>4 publications with DCN1 and Lung Neoplasms
Cell Transformation, Neoplastic Antibodies	>4 publications with DCN1 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-DCN1 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>7 publications with DCN1 and Lung
Brain Antibodies	>2 publications with DCN1 and Brain
Bone Antibodies	>1 publications with DCN1 and Bone
Testis Antibodies	>1 publications with DCN1 and Testis