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Insulin-Like Growth Factor-Binding Protein 1 (IGFBP1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1498237

This gene is a member of the Insulin-like growth factor-binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a type-I thyroglobulin domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the… More details

$270 / 0.05 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Insulin-like growth factor-binding protein 1 (IGFBP1), Monoclonal Antibody
Full Product Name
Mouse anti- Human Insulin-like growth factor-binding protein 1(IGFBP1) monoclonal Antibody
Product Gene Name
Product Synonym Names
IGFBP1; Insulin-like growth factor-binding protein 1; IGF-binding protein 1
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Species Reactivity
Human. Other species are not tested. Please decide the specificity by homology
Purity/Purification
>95%, Protein G Purified
Specificity
Specific for human IGFBP1 denatured and native forms.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
27,904 Da
OMIM
146730
3D Structure
ModBase 3D Structure for P08833
Storage Buffer
Preservative: 15mmol/L NaN3
Constituents: 0.1mol/L Nacl
Conjugate
Non-conjugated
Immunogen
Recombinant Human IGFBP1 Protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-25257
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IGFBP1 antibody
ELISA (EIA), Western Blot (WB)

Western Blot (WB) of anti-IGFBP1 antibody

All lanes: Mouse anti- Human Insulin-like growth factor-binding protein 1 monoclonal antibody at 1ug/ml
Lane 1:Pyrolysis liquid human placental tissue 7.5ug/ml
Lane 2:Pyrolysis liquid human placental tissue 3.25ug/ml
Lane 3:IGFBP1 transfected SF9 cell lysate
Lane 4:human amniotic fluid
Secondary Goat polyclonal to Mouse IgG at 1/5000 dilution
Predicted band size: 28kd
Observed band size: 35kd
Mouse Anti-IGFBP1 Monoclonal Antibody – Cat# MBS1498237

Other Notes

Small volumes of anti-IGFBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGFBP1 purchase

MBS1498237 is an antibody targeting IGFBP1. Also known as Mouse anti- Human Insulin-like growth factor-binding protein 1(IGFBP1) monoclonal Antibody. Reactive in Human. Other species are not tested. Please decide the specificity by homology. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IGFBP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
insulin-like growth factor-binding protein 1
NCBI Official Synonym Full Names
insulin like growth factor binding protein 1
NCBI Official Symbol
IGFBP1
NCBI Official Synonym Symbols
AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1
UniProt Protein Name
Insulin-like growth factor-binding protein 1
UniProt Synonym Protein Names
Placental protein 12; PP12
UniProt Gene Name
IGFBP1
UniProt Synonym Gene Names
IBP1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12
UniProt Entry Name
IBP1_HUMAN
NCBI Protein Information
insulin-like growth factor-binding protein 1

NCBI Summary for IGFBP1

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]
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UniProt Comments for IGFBP1

IGFBP1: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: extracellular region; extracellular space

Molecular Function: insulin-like growth factor binding; insulin-like growth factor I binding; insulin-like growth factor II binding

Biological Process: cellular protein metabolic process; insulin receptor signaling pathway; positive regulation of cell growth; regulation of insulin-like growth factor receptor signaling pathway; signal transduction; tissue regeneration; unfolded protein response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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