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Mitochondrial Import Receptor Subunit TOM20 Homolog (TOMM20) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1498384

Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer… More details

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Product Overview

Online Datasheet in PDF
Product Name
Mitochondrial import receptor subunit TOM20 homolog (TOMM20), Polyclonal Antibody
Full Product Name
Rabbit anti-human Mitochondrial import receptor subunit TOM20 homolog polyclonal Antibody(TOMM20)
Product Gene Name
anti-TOMM20 antibody
Product Synonym Names
Mitochondrial 20 kDa outer membrane protein; Outer mitochondrial membrane receptor Tom20; TOMM20; KIAA0016
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
16,298 Da
OMIM
601848
3D Structure
ModBase 3D Structure for Q15388
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Mitochondrial import receptor subunit TOM20 homolog protein(20-145aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-11021 / sc-11415
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TOMM20 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TOMM20 antibody
Recommended dilution: WB:1:500-5000
IHC:1:20-1:200

Western Blot (WB) of anti-TOMM20 antibody

All lanes: Mitochondrial import receptor subunit TOM20 homolog antibody at 3ug/ml
Lane 1:mouse brain tissue
Lane 2:Hela whole cell lysate
Lane 3:mouse liver tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 16kDa
Observed band size: 16kDa
Rabbit Anti-TOMM20 Polyclonal Antibody – Cat# MBS1498384

Immunohistochemistry (IHC) of anti-TOMM20 antibody

Immunohistochemistry of paraffin-embedded human kidney using MBS1498384 at dilution 1:100
Rabbit Anti-TOMM20 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1498384

Immunohistochemistry (IHC) of anti-TOMM20 antibody

Immunofluorescent analysis of HepG2 cells using MBS1498384 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Rabbit Anti-TOMM20 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1498384

Other Notes

Small volumes of anti-TOMM20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TOMM20 purchase

MBS1498384 is an antibody targeting TOMM20. Also known as Rabbit anti-human Mitochondrial import receptor subunit TOM20 homolog polyclonal Antibody(TOMM20). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TOMM20. It may not necessarily be applicable to this product.

NCBI GI #
7657257
NCBI GeneID
9804
NCBI Accession #
NP_055580.1
UniProt Primary Accession #
Q15388
UniProt Secondary Accession #
Q498B3; Q6IBT4; A8K195
UniProt Related Accession #
Q15388; AAB35420
GenBank Nucleotide #
NM_014765.2
NCBI Official Full Name
mitochondrial import receptor subunit TOM20 homolog
NCBI Official Synonym Full Names
translocase of outer mitochondrial membrane 20 homolog (yeast)
NCBI Official Symbol
TOMM20
NCBI Official Synonym Symbols
MAS20; MOM19; TOM20
UniProt Protein Name
Mitochondrial import receptor subunit TOM20 homolog
UniProt Synonym Protein Names
Mitochondrial 20 kDa outer membrane protein; Outer mitochondrial membrane receptor Tom20
Protein Family
Mitochondrial import receptor
UniProt Gene Name
TOMM20
UniProt Synonym Gene Names
KIAA0016
UniProt Entry Name
TOM20_HUMAN
NCBI Protein Information
mitochondrial import receptor subunit TOM20 homolog

UniProt Comments for TOMM20

TOM20: Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Belongs to the Tom20 family.

Protein type: Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q42

Cellular Component: integral to mitochondrial outer membrane; mitochondrial outer membrane; mitochondrial outer membrane translocase complex; mitochondrion

Molecular Function: mitochondrion targeting sequence binding; P-P-bond-hydrolysis-driven protein transmembrane transporter activity; protein binding; protein channel activity; unfolded protein binding

Biological Process: cellular protein metabolic process; cytoplasmic tRNA import into mitochondrion; macroautophagy; macromitophagy; protein import into mitochondrial matrix; protein targeting to mitochondrion
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Research Articles on TOMM20

1. Tom20 was ubiquitously distributed in the organ of Corti, allowing well-delineated visualization of inner and outer hair cells. In the inner ear of aged subjects with Meniere's disease, there was decreased expression of Tom20.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TOMM20 antibody

 Reference Product  PubMed Publications
 TOMM22 antibody  >7 publications with TOMM20 and TOMM22
 PINK1 antibody  >6 publications with TOMM20 and PINK1
 TOMM70A antibody  >3 publications with TOMM20 and TOMM70A
 TIMM44 antibody  >2 publications with TOMM20 and TIMM44
 TOMM40 antibody  >2 publications with TOMM20 and TOMM40
 MTX1 antibody  >1 publications with TOMM20 and MTX1

Pathways associated with anti-TOMM20 antibody

 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Mitochondrial Protein Import Pathway antibodies  Mitochondrial Protein Import Pathway Diagram
 Mitophagy Pathway antibodies  Mitophagy Pathway Diagram
 Pink/Parkin Mediated Mitophagy Pathway antibodies  Pink/Parkin Mediated Mitophagy Pathway Diagram

Diseases associated with anti-TOMM20 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with TOMM20 and Inflammation
 Necrosis Antibodies  >2 publications with TOMM20 and Necrosis

Organs/Tissues associated with anti-TOMM20 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >10 publications with TOMM20 and Muscle
 Liver Antibodies  >9 publications with TOMM20 and Liver
 Brain Antibodies  >4 publications with TOMM20 and Brain
 Heart Antibodies  >3 publications with TOMM20 and Heart
 Thyroid Antibodies  >3 publications with TOMM20 and Thyroid
 Lymph Antibodies  >2 publications with TOMM20 and Lymph
 Nerve Antibodies  >2 publications with TOMM20 and Nerve
 Lymph Node Antibodies  >2 publications with TOMM20 and Lymph Node
 Vascular Antibodies  >1 publications with TOMM20 and Vascular
 Pancreas Antibodies  >1 publications with TOMM20 and Pancreas
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