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RNMTL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1498450

S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RNMTL1, Polyclonal Antibody
Full Product Name
RNMTL1 Antibody, HRP conjugated
Product Gene Name
Product Synonym Names
rRNA methyltransferase 3; mitochondrial1 Publication; RNMTL11; 16S rRNA (guanosine(1370)-2'-O)-methyltransferase1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: RNMTL1 (MBS1499091)
HRP Conjugated Antibody: RNMTL1 (MBS1498450)
Molecular Weight
47,020 Da
OMIM
612600
3D Structure
ModBase 3D Structure for Q9HC36
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
HRP
Immunogen
Recombinant human rRNA methyltransferase 3, mitochondrial protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162114 / sc-162115
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RNMTL1 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-RNMTL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RNMTL1 purchase

MBS1498450 is an antibody targeting RNMTL1. Also known as RNMTL1 Antibody, HRP conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RNMTL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rRNA methyltransferase 3, mitochondrial isoform 1
NCBI Official Synonym Full Names
RNA methyltransferase like 1
NCBI Official Symbol
RNMTL1
NCBI Official Synonym Symbols
MRM3; RMTL1
UniProt Protein Name
rRNA methyltransferase 3, mitochondrial
UniProt Synonym Protein Names
16S rRNA (guanosine(1370)-2'-O)-methyltransferase
UniProt Gene Name
RNMTL1
UniProt Entry Name
MRM3_HUMAN
NCBI Protein Information
rRNA methyltransferase 3, mitochondrial

NCBI Summary for RNMTL1

Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
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UniProt Comments for RNMTL1

RNMTL1: Probable RNA methyltransferase. Belongs to the RNA methyltransferase TrmH family.

Protein type: EC 2.1.1.-; RNA-binding; Methyltransferase

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: mitochondrion

Molecular Function: methyltransferase activity; protein binding; RNA binding; RNA methyltransferase activity

Biological Process: RNA methylation; rRNA processing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RNMTL1 antibody

Organs/Tissues associated with anti-RNMTL1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with RNMTL1 and Blood
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