Rabbit Anti-STXBP4 Polyclonal Antibody – Cat# MBS1499390

Western blot
All lanes: STXBP4 antibody at 10ug/ml+PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 62,27 kDa
Observed band size: 62 kDa

STXBP4 Antibody – Rabbit Polyclonal

Name: STXBP4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1499390
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1499390

Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2.… More details

$230 / 0.05 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

STXBP4, Polyclonal Antibody

Full Product Name

STXBP4 Antibody

Product Gene Name

anti-STXBP4 antibody

Product Synonym Names

Syntaxin 4-interacting protein; STX4-interacting protein; Synip; STXBP4

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

Antigen Affinity Purified

Preparation and Storage

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Molecular Weight

26,974 Da

OMIM

610415

3D Structure

ModBase 3D Structure for Q6ZWJ1

Storage Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Conjugate

Non-conjugated

Immunogen

Recombinant human Syntaxin-binding protein 4 protein (344-553aa)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-STXBP4 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-STXBP4 antibody

Recommended dilution: WB:1:500-5000

Other Notes

Small volumes of anti-STXBP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STXBP4 purchase

MBS1499390 is an antibody targeting STXBP4. Also known as STXBP4 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STXBP4. It may not necessarily be applicable to this product.

NCBI GI #

63999048

NCBI GeneID

252983

NCBI Accession #

NP_848604.3

UniProt Primary Accession #

Q6ZWJ1

UniProt Secondary Accession #

Q8IVZ5

UniProt Related Accession #

Q6ZWJ1

GenBank Nucleotide #

NM_178509.5

NCBI Official Full Name

syntaxin-binding protein 4

NCBI Official Synonym Full Names

syntaxin binding protein 4

NCBI Official Symbol

STXBP4

NCBI Official Synonym Symbols

Synip

UniProt Protein Name

Syntaxin-binding protein 4

UniProt Synonym Protein Names

Syntaxin 4-interacting protein; STX4-interacting protein; Synip

Protein Family

Syntaxin-binding protein

UniProt Gene Name

STXBP4

UniProt Synonym Gene Names

STX4-interacting protein; Synip

UniProt Entry Name

STXB4_HUMAN

NCBI Protein Information

syntaxin-binding protein 4

UniProt Comments for STXBP4

STXBP4: Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose. Interacts with STX4A. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: cytoplasm; intermediate filament cytoskeleton; nucleoplasm

Molecular Function: protein binding; syntaxin binding

Biological Process: glucose transport; insulin receptor signaling pathway; protein stabilization; protein targeting; response to DNA damage stimulus

Research Articles on STXBP4

1. meta-analysis suggested that polymorphism STXBP4/COX11 rs6504950 variant was significantly associated with breast cancer risk; the A allele of rs6504950 decreased the risk of breast cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-STXBP4 antibody

Reference Product	PubMed Publications
SLC2A4 antibody	>6 publications with STXBP4 and SLC2A4
VAMP2 antibody	>3 publications with STXBP4 and VAMP2
SNAP23 antibody	>2 publications with STXBP4 and SNAP23
AKT3 antibody	>2 publications with STXBP4 and AKT3
AKT1 antibody	>2 publications with STXBP4 and AKT1
AKT2 antibody	>2 publications with STXBP4 and AKT2
STX4 antibody	>2 publications with STXBP4 and STX4

Pathways associated with anti-STXBP4 antibody

Products by Pathway	Pathway Diagram
Insulin Signaling Pathway antibodies	Insulin Signaling Pathway Diagram
Insulin-mediated Glucose Transport Pathway antibodies	Insulin-mediated Glucose Transport Pathway Diagram

Diseases associated with anti-STXBP4 antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>3 publications with STXBP4 and Breast Neoplasms
Inflammation Antibodies	>1 publications with STXBP4 and Inflammation

Organs/Tissues associated with anti-STXBP4 antibody

Organ/Tissue Name	Pubmed Publications
Pancreas Antibodies	>1 publications with STXBP4 and Pancreas
Kidney Antibodies	>1 publications with STXBP4 and Kidney