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Actin-Related Protein 3b (ACTR3B) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1499432

Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the… More details

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Product Overview

Online Datasheet in PDF
Product Name
Actin-related protein 3B (ACTR3B), Polyclonal Antibody
Full Product Name
Rabbit anti-human Actin-related protein 3B polyclonal Antibody(ACTR3B)
Product Gene Name
Product Synonym Names
ARP3-beta; Actin-like protein 3B; Actin-related protein ARP4; ACTR3B; ARP11; ARP4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
39,698 Da
3D Structure
ModBase 3D Structure for Q9P1U1
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Actin-related protein 3B protein (189-418aa)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ACTR3B antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ACTR3B antibody
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200

Western Blot (WB) of anti-ACTR3B antibody

All lanes: Actin-related protein 3B antibody at 8ug/ml+HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 48,38,40 kDa
Observed band size: 48 kDa
Rabbit Anti-ACTR3B Polyclonal Antibody – Cat# MBS1499432

Immunohistochemistry (IHC) of anti-ACTR3B antibody

Immunohistochemistry of paraffin-embedded human tonsil using MBS1499432 at dilution 1:100
Rabbit Anti-ACTR3B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1499432

Immunohistochemistry (IHC) of anti-ACTR3B antibody

Immunohistochemistry of paraffin-embedded human kidney using MBS1499432 at dilution 1:100
Rabbit Anti-ACTR3B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1499432

Other Notes

Small volumes of anti-ACTR3B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ACTR3B purchase

MBS1499432 is an antibody targeting ACTR3B. Also known as Rabbit anti-human Actin-related protein 3B polyclonal Antibody(ACTR3B). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ACTR3B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
actin-related protein 3B isoform 2
NCBI Official Synonym Full Names
ARP3 actin-related protein 3 homolog B (yeast)
NCBI Official Symbol
ACTR3B
NCBI Official Synonym Symbols
ARP11; ARP3BETA
UniProt Protein Name
Actin-related protein 3B
UniProt Synonym Protein Names
ARP3-beta; Actin-like protein 3B; Actin-related protein ARP4
Protein Family
UniProt Gene Name
ACTR3B
UniProt Synonym Gene Names
ARP11; ARP4
UniProt Entry Name
ARP3B_HUMAN
NCBI Protein Information
actin-related protein 3B

NCBI Summary for ACTR3B

This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
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UniProt Comments for ACTR3B

ACTR3B: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors. Belongs to the actin family. ARP3 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: Arp2/3 protein complex; cell projection; cytoplasm

Molecular Function: actin binding; ATP binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-ACTR3B antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >2 publications with ACTR3B and Lung
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