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CDK16 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1499828

Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron… More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CDK16, Polyclonal Antibody
Full Product Name
CDK16 Antibody
Product Gene Name
anti-CDK16 antibody
Product Synonym Names
Cell division protein kinase 16; PCTAIRE-motif protein kinase 1; Serine/threonine-protein kinase PCTAIRE-1; CDK16; PCTAIRE1; PCTK1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
56,375 Da
OMIM
311550
3D Structure
ModBase 3D Structure for Q00536
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Cyclin-dependent kinase 16 protein (277-496aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-174 / sc-22775
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CDK16 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CDK16 antibody
Recommended dilution: WB:1:200-1000
IHC:1:20-1:200

Western Blot (WB) of anti-CDK16 antibody

Western blot
All lanes: CDK16 antibody at 5ug/ml
Lane 1:mouse brain tissue
Lane 2:mouse small intestine tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 56,64,57 kDa
Observed band size: 56 kDa
Rabbit Anti-CDK16 Polyclonal Antibody – Cat# MBS1499828

Immunohistochemistry (IHC) of anti-CDK16 antibody

Immunohistochemistry of paraffin-embedded human placenta tissue
using MBS1499828 at dilution 1:100
Rabbit Anti-CDK16 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1499828

Other Notes

Small volumes of anti-CDK16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK16 purchase

MBS1499828 is an antibody targeting CDK16. Also known as CDK16 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK16. It may not necessarily be applicable to this product.

NCBI GI #
281427158
NCBI GeneID
5127
NCBI Accession #
NP_001163931.1
UniProt Primary Accession #
Q00536
UniProt Secondary Accession #
A8K280; B7Z7C8; J3KN74; J3KQP7
UniProt Related Accession #
Q00536
GenBank Nucleotide #
NM_001170460.1
NCBI Official Full Name
cyclin-dependent kinase 16 isoform 3
NCBI Official Synonym Full Names
cyclin-dependent kinase 16
NCBI Official Symbol
CDK16
NCBI Official Synonym Symbols
PCTK1; PCTAIRE; PCTAIRE1; PCTGAIRE
UniProt Protein Name
Cyclin-dependent kinase 16
UniProt Synonym Protein Names
Cell division protein kinase 16; PCTAIRE-motif protein kinase 1; Serine/threonine-protein kinase PCTAIRE-1
Protein Family
Cyclin-dependent kinase
UniProt Gene Name
CDK16
UniProt Synonym Gene Names
PCTAIRE1; PCTK1
UniProt Entry Name
CDK16_HUMAN
NCBI Protein Information
cyclin-dependent kinase 16

NCBI Summary for CDK16

The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]
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UniProt Comments for CDK16

CDK16: May play a role in signal transduction cascades in terminally differentiated cells. Found in a complex containing CABLES1, CDK17 and TDRD7. Interacts with YWHAH, YWHAQ and YWHAZ. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Cell cycle regulation; EC 2.7.11.22; Protein kinase, CMGC; Motility/polarity/chemotaxis; CMGC group; CDK family; CDK/TAIRE subfamily; TAIRE subfamily

Chromosomal Location of Human Ortholog: Xp11

Cellular Component: cell junction; cytoplasm; extrinsic to internal side of plasma membrane; microtubule cytoskeleton; neuron projection; plasma membrane; synaptic vesicle

Molecular Function: ATP binding; cyclin-dependent protein kinase activity; protein binding; protein serine/threonine kinase activity

Biological Process: exocytosis; growth hormone secretion; neurite development; protein amino acid phosphorylation; regulation of cell cycle; spermatogenesis
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Research Articles on CDK16

1. Activation of PCTAIRE-1 is mediated through interaction with the phosphorylated form of cyclin Y in complex with 14-3-3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CDK16 antibody

 Reference Product  PubMed Publications
 CCNY antibody  >4 publications with CDK16 and CCNY
 MTOR antibody  >1 publications with CDK16 and MTOR

Diseases associated with anti-CDK16 antibody

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >2 publications with CDK16 and Brain Diseases
 Nervous System Diseases Antibodies  >1 publications with CDK16 and Nervous System Diseases
 Infertility, Female Antibodies  >1 publications with CDK16 and Infertility, Female
 Infertility, Male Antibodies  >1 publications with CDK16 and Infertility, Male

Organs/Tissues associated with anti-CDK16 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with CDK16 and Brain
 Testis Antibodies  >4 publications with CDK16 and Testis
 Epididymis Antibodies  >1 publications with CDK16 and Epididymis
 Pancreas Antibodies  >1 publications with CDK16 and Pancreas
 Heart Antibodies  >1 publications with CDK16 and Heart
 Muscle Antibodies  >1 publications with CDK16 and Muscle
 Prostate Antibodies  >1 publications with CDK16 and Prostate
 Embryonic Tissue Antibodies  >1 publications with CDK16 and Embryonic Tissue
 Lung Antibodies  >1 publications with CDK16 and Lung
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