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FGF4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150052

FGF4 Antibody: Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FGF4, Polyclonal Antibody
Full Product Name
FGF4 Antibody
Product Gene Name
anti-FGF4 antibody
Product Synonym Names
FGF4; HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-4; HST; KS3; Fibroblast growth factor 4; Heparin secretory-transforming protein 1; FGF-4; fibroblast growth factor 4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid; FGF4 Antibody is supplied in PBS containing 0.02% sodium azide.
Purity/Purification
FGF4 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
FGF4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
FGF4 peptide (MBS152765) is used for blocking the activity of FGF4 antibody (MBS150052)
OMIM
164980
3D Structure
ModBase 3D Structure for P08620
Immunogen
FGF4 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of the human FGF4. The immunogen is located within the last 50 amino acids of FGF4
Homology
Predicted species reactivity based on immunogen sequence: Bovine (94%), Chicken (88%)
Applications Tested/Suitable for anti-FGF4 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-FGF4 antibody
Optimal dilutions for each application should be determined by end user

Western Blot (WB) of anti-FGF4 antibody

Western blot analysis of FGF4 in NIH 3T3 cell lysate with FGF4 antibody at (A) 0.5 and (B) 1 μg/mL.
Rabbit Anti-FGF4 Polyclonal Antibody – Cat# MBS150052

Immunocytochemistry (IHC) of anti-FGF4 antibody

Immunocytochemistry of FGF4 in 3T3 cells with FGF4 antibody at 2.5 μg/mL.
Rabbit Anti-FGF4 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS150052

Immunofluorescence (IF) of anti-FGF4 antibody

Immunofluorescence of FGF4 in 3T3 cells with FGF4 antibody at 2.5 μg/mL.
Rabbit Anti-FGF4 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150052

Other Notes

Small volumes of anti-FGF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGF4 purchase

MBS150052 is an antibody targeting FGF4. Also known as FGF4 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FGF4. It may not necessarily be applicable to this product.

NCBI GI #
122750
NCBI GeneID
2249
NCBI Accession #
P08620.1
UniProt Primary Accession #
P08620
UniProt Secondary Accession #
B7U994
UniProt Related Accession #
P08620; AAB21430
NCBI Official Full Name
Fibroblast growth factor 4
NCBI Official Synonym Full Names
fibroblast growth factor 4
NCBI Official Symbol
FGF4
NCBI Official Synonym Symbols
HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-4
UniProt Protein Name
Fibroblast growth factor 4
UniProt Synonym Protein Names
Heparin secretory-transforming protein 1; HST; HST-1; HSTF-1; Heparin-binding growth factor 4; HBGF-4; Transforming protein KS3
Protein Family
Fibroblast growth factor
UniProt Gene Name
FGF4
UniProt Synonym Gene Names
HST; HSTF1; KS3; FGF-4; HST; HST-1; HSTF-1; HBGF-4
UniProt Entry Name
FGF4_HUMAN
NCBI Protein Information
fibroblast growth factor 4; FGF-4; HSTF-1; oncogene HST; kaposi sarcoma oncogene; transforming protein KS3; heparin-binding growth factor 4; heparin secretory transforming protein 1; heparin secretory-transforming protein 1; fibroblast growth factor 4 splice isoform; human stomach cancer, transforming factor from FGF-related oncogene

NCBI Summary for FGF4

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008]
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UniProt Comments for FGF4

Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis.

Research Articles on FGF4

1. Data show that the interaction between Artd1 and Sox2 is crucial for the first steps of the reprogramming process and that early expression of Fgf4 is an essential component for the successful generation of iPSCs.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FGF4 antibody

 Reference Product  PubMed Publications
 SHH antibody  >78 publications with FGF4 and SHH
 SOX2 antibody  >69 publications with FGF4 and SOX2
 FGFR2 antibody  >52 publications with FGF4 and FGFR2
 FGFR1 antibody  >38 publications with FGF4 and FGFR1
 CTNNB1 antibody  >17 publications with FGF4 and CTNNB1
 FGFR3 antibody  >17 publications with FGF4 and FGFR3
 FGFR4 antibody  >17 publications with FGF4 and FGFR4
 MSX1 antibody  >12 publications with FGF4 and MSX1
 LEF1 antibody  >11 publications with FGF4 and LEF1
 GREM1 antibody  >5 publications with FGF4 and GREM1

Pathways associated with anti-FGF4 antibody

 Products by Pathway  Pathway Diagram
 Activated Point Mutants Of FGFR2 Pathway antibodies  Activated Point Mutants Of FGFR2 Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 FGFR Ligand Binding And Activation Pathway antibodies  FGFR Ligand Binding And Activation Pathway Diagram

Diseases associated with anti-FGF4 antibody

 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >39 publications with FGF4 and Skin Diseases
 Breast Neoplasms Antibodies  >39 publications with FGF4 and Breast Neoplasms
 Disease Models, Animal Antibodies  >26 publications with FGF4 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >25 publications with FGF4 and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >21 publications with FGF4 and Neoplasms, Experimental
 Neoplasm Metastasis Antibodies  >20 publications with FGF4 and Neoplasm Metastasis
 Neovascularization, Pathologic Antibodies  >19 publications with FGF4 and Neovascularization, Pathologic
 Nervous System Diseases Antibodies  >17 publications with FGF4 and Nervous System Diseases
 Brain Diseases Antibodies  >14 publications with FGF4 and Brain Diseases
 Necrosis Antibodies  >10 publications with FGF4 and Necrosis

Organs/Tissues associated with anti-FGF4 antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >141 publications with FGF4 and Embryonic Tissue
 Testis Antibodies  >11 publications with FGF4 and Testis
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