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CASKIN2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150096

CASKIN2 Antibody: Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting protein) interact with… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CASKIN2, Polyclonal Antibody
Full Product Name
CASKIN2 Antibody
Product Gene Name
Product Synonym Names
CASKIN2; ANKS5B; KIAA1139; Caskin-2; CASK-interacting protein 2; CASK interacting protein 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
CASKIN2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
CASKIN2 antibody is predicted to not cross-react with other CASKIN family members. Three isoforms of CASKIN2 are known to exist; this antibody will not detect the shortest isoform.
Preparation and Storage
CASKIN2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
CASKIN2 peptide (MBS152552) is used for blocking the activity of CASKIN2 antibody (MBS150096)
Molecular Weight
118,157 Da
OMIM
612185
3D Structure
ModBase 3D Structure for Q8WXE0
Conjugate
Unconjugated
Immunogen
CASKIN2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human CASKIN2.
Buffer
CASKIN2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-CASKIN2 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-CASKIN2 antibody
CASKIN2 antibody can be used for detection of EPAC1 by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 mug/mL. For immunofluorescence start at 5 mug/mL.

Western Blot (WB) of anti-CASKIN2 antibody

Western blot analysis of CASKIN2 HeLa cell tissue lysate with CASKIN2 antibody at 1 μg/mL.
Rabbit Anti-CASKIN2 Polyclonal Antibody – Cat# MBS150096

Immunocytochemistry (IHC) of anti-CASKIN2 antibody

Immunocytochemistry of CASKIN2 in HeLa cells with CASKIN2 antibody at 2.5 μg/mL.
Rabbit Anti-CASKIN2 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS150096

Immunofluorescence (IF) of anti-CASKIN2 antibody

Immunofluorescence of CASKIN2 in HeLa cells with CASKIN2 antibody at 20 μg/mL.
Rabbit Anti-CASKIN2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150096

Other Notes

Small volumes of anti-CASKIN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CASKIN2 purchase

MBS150096 is an antibody targeting CASKIN2. Also known as CASKIN2 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CASKIN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
caskin-2 isoform a
NCBI Official Synonym Full Names
CASK interacting protein 2
NCBI Official Symbol
CASKIN2
NCBI Official Synonym Symbols
ANKS5B
UniProt Protein Name
Caskin-2
UniProt Synonym Protein Names
CASK-interacting protein 2
Protein Family
UniProt Gene Name
CASKIN2
UniProt Synonym Gene Names
KIAA1139
UniProt Entry Name
CSKI2_HUMAN
NCBI Protein Information
caskin-2

NCBI Summary for CASKIN2

This gene encodes a large protein that contains six ankyrin repeats, as well as a Src homology 3 (SH3) domain and two sterile alpha motif (SAM) domains, which may be involved in protein-protein interactions. The C-terminal portion of this protein is proline-rich and contains a conserved region. A related protein interacts with calcium/calmodulin-dependent serine protein kinase (CASK). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
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UniProt Comments for CASKIN2

CASKIN2: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: cytoplasm

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CASKIN2 antibody

 Reference Product  PubMed Publications
 CASK antibody  >1 publications with CASKIN2 and CASK

Organs/Tissues associated with anti-CASKIN2 antibody

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