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ATOH8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150120

ATOH8 Antibody: Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ATOH8, Polyclonal Antibody
Full Product Name
ATOH8 Antibody
Product Gene Name
anti-ATOH8 antibody
Product Synonym Names
ATOH8; HATH6; bHLHa21; ATH6; BHLHA21; Protein atonal homolog 8; Class A basic helix-loop-helix protein 21; atonal homolog 8 (Drosophila)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
ATOH8 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
ATOH8 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
ATOH8 peptide (MBS152461) is used for blocking the activity of ATOH8 antibody (MBS150120)
Molecular Weight
45,801 Da
3D Structure
ModBase 3D Structure for Q96SQ7
Conjugate
Unconjugated
Immunogen
ATOH8 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ATOH8.
Buffer
ATOH8 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-ATOH8 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ATOH8 antibody
ATOH8 antibody can be used for detection of ATOH8 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL.

Western Blot (WB) of anti-ATOH8 antibody

Western blot analysis of ATOH8 in A-20 cell lysate with ATOH8 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-ATOH8 Polyclonal Antibody – Cat# MBS150120

Immunohistochemistry (IHC) of anti-ATOH8 antibody

Immunohistochemistry of ATOH8 in mouse brain tissue with ATOH8 antibody at 5 μg/mL.
Rabbit Anti-ATOH8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150120

Other Notes

Small volumes of anti-ATOH8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATOH8 purchase

MBS150120 is an antibody targeting ATOH8. Also known as ATOH8 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ATOH8. It may not necessarily be applicable to this product.

NCBI GI #
226498192
NCBI GeneID
84913
NCBI Accession #
NP_116216
UniProt Primary Accession #
Q96SQ7
UniProt Secondary Accession #
Q504S2; Q659B0
UniProt Related Accession #
Q96SQ7
GenBank Nucleotide #
NM_032827.6
NCBI Official Full Name
protein atonal homolog 8
NCBI Official Synonym Full Names
atonal homolog 8 (Drosophila)
NCBI Official Symbol
ATOH8
NCBI Official Synonym Symbols
HATH6; bHLHa21
UniProt Protein Name
Protein atonal homolog 8
UniProt Synonym Protein Names
Class A basic helix-loop-helix protein 21; bHLHa21; Helix-loop-helix protein hATH-6; hATH6
Protein Family
Protein atonal
UniProt Gene Name
ATOH8
UniProt Synonym Gene Names
ATH6; BHLHA21; bHLHa21; hATH6
UniProt Entry Name
ATOH8_HUMAN
NCBI Protein Information
protein atonal homolog 8; atonal homolog 6; helix-loop-helix protein hATH-6; class A basic helix-loop-helix protein 21; basic helix loop helix transcription factor 6; basic helix-loop-helix transcription factor 6

UniProt Comments for ATOH8

ATOH8: Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: nucleus

Molecular Function: protein dimerization activity; DNA binding

Biological Process: nervous system development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; cell differentiation
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Research Articles on ATOH8

1. Data show that in ATOH8 was hosted in one chromosome which is a fusion product of two orthologous chromosomes in non-human. primates.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ATOH8 antibody

 Reference Product  PubMed Publications
 SMAD7 antibody  >1 publications with ATOH8 and SMAD7
 BMP6 antibody  >1 publications with ATOH8 and BMP6

Diseases associated with anti-ATOH8 antibody

 Disease Name  Pubmed Publications
 Hypertrophy Antibodies  >1 publications with ATOH8 and Hypertrophy
 Kidney Diseases Antibodies  >1 publications with ATOH8 and Kidney Diseases

Organs/Tissues associated with anti-ATOH8 antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >6 publications with ATOH8 and Embryonic Tissue
 Muscle Antibodies  >5 publications with ATOH8 and Muscle
 Eye Antibodies  >2 publications with ATOH8 and Eye
 Kidney Antibodies  >2 publications with ATOH8 and Kidney
 Liver Antibodies  >2 publications with ATOH8 and Liver
 Brain Antibodies  >2 publications with ATOH8 and Brain
 Bladder Antibodies  >1 publications with ATOH8 and Bladder
 Vascular Antibodies  >1 publications with ATOH8 and Vascular
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