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FNIP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150131

MBS150131 is an antibody targeting FNIP2. Also known as FNIP2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FNIP2, Polyclonal Antibody
Full Product Name
FNIP2 Antibody
Product Gene Name
anti-FNIP2 antibody
Product Synonym Names
FNIP2; FNIPL; MAPO1; FNIPL; KIAA1450; Folliculin-interacting protein 2; FNIP1-like protein; folliculin interacting protein 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
FNIP2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.
Preparation and Storage
FNIP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
FNIP2 peptide (MBS152281) is used for blocking the activity of FNIP2 antibody (MBS150131)
OMIM
612768
3D Structure
ModBase 3D Structure for Q9P278
Conjugate
Unconjugated
Immunogen
FNIP2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human FNIP2.
The immunogen is located within amino acids 860-910 ofNIP2.
Buffer
FNIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-FNIP2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-p)
Application Notes for anti-FNIP2 antibody
Optimal dilutions to be determined by the researcher.

Western Blot (WB) of anti-FNIP2 antibody

Western blot analysis of FNIP2 in rat skeletal muscle lysate with FNIP2 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-FNIP2 Polyclonal Antibody – Cat# MBS150131

Immunohistochemistry (IHC) of anti-FNIP2 antibody

Immunohistochemistry of FNIP2 in mouse skeletal muscle tissue with FNIP2 antibody at 5 μg/mL.
Rabbit Anti-FNIP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150131

Other Notes

Small volumes of anti-FNIP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FNIP2. It may not necessarily be applicable to this product.

NCBI GI #
154689769
NCBI GeneID
57600
NCBI Accession #
NP_065891
UniProt Primary Accession #
Q9P278
UniProt Secondary Accession #
Q05DC3; Q96I31; Q9H994
UniProt Related Accession #
Q9P278
GenBank Nucleotide #
NM_020840.1
NCBI Official Full Name
folliculin-interacting protein 2
NCBI Official Synonym Full Names
folliculin interacting protein 2
NCBI Official Symbol
FNIP2
NCBI Official Synonym Symbols
FNIPL; MAPO1
UniProt Protein Name
Folliculin-interacting protein 2
UniProt Synonym Protein Names
FNIP1-like protein; O6-methylguanine-induced apoptosis 1 protein
Protein Family
Folliculin-interacting protein
UniProt Gene Name
FNIP2
UniProt Synonym Gene Names
FNIPL; KIAA1450; MAPO1
UniProt Entry Name
FNIP2_HUMAN
NCBI Protein Information
folliculin-interacting protein 2; FNIP1-like protein; O6-methylguanine-induced apoptosis 1 protein

UniProt Comments for FNIP2

FNIP2: May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. Belongs to the FNIP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 4q32.1

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; microtubule organizing center

Molecular Function: protein binding

Biological Process: regulation of protein amino acid phosphorylation; DNA damage response, signal transduction resulting in induction of apoptosis; negative regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; positive regulation of peptidyl-serine phosphorylation
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Research Articles on FNIP2

1. this study obtained evidence to show that stabilization of MAPO1 is regulated through its specific interaction with folliculin and AMPK.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FNIP2 antibody

 Reference Product  PubMed Publications
 FLCN antibody  >11 publications with FNIP2 and FLCN

Diseases associated with anti-FNIP2 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >3 publications with FNIP2 and Kidney Diseases

Organs/Tissues associated with anti-FNIP2 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >4 publications with FNIP2 and Kidney
 Lung Antibodies  >2 publications with FNIP2 and Lung
 Nerve Antibodies  >1 publications with FNIP2 and Nerve
 Brain Antibodies  >1 publications with FNIP2 and Brain
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