• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SLC39A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150157

ZIP1 Antibody: ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ZIP1 (SLC39A1), Polyclonal Antibody
Full Product Name
ZIP1 Antibody
Product Gene Name
Product Synonym Names
ZIP1 Antibody: ZIP1, ZIRTL, IRT1, ZIP1, CGI-08, CGI-71, Zinc transporter ZIP1, Solute carrier family 39 member 1, ZIP-1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid; ZIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purity/Purification
ZIP1 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least two isoforms of ZIP1 are known to exist; this antibody will detect both isoforms. ZIP1 antibody is predicted not to cross-react with other ZIP family proteins.
Preparation and Storage
ZIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
ZIP1 peptide (MBS152636) is used for blocking the activity of ZIP1 antibody (MBS150157)
Molecular Weight
Predicted: 13, 36 kDa
Observed: 38 kDa
OMIM
604740
3D Structure
ModBase 3D Structure for Q9NY26
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (88%)
Immunogen
ZIP1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human ZIP1.
The immunogen is located within amino acids 40 - 90 of ZIP1.
Positive Control
1) Cat. No. MBS151592 - Mouse Kidney Tissue Lysate
2) Cat. No. MBS154338 - Human Kidney Tissue Slide
Applications Tested/Suitable for anti-SLC39A1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF)
Application Notes for anti-SLC39A1 antibody
ZIP1 antibody can be used for detection of ZIP1 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.

Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Optimal dilutions for each application to be determined by the researcher.

Western Blot (WB) of anti-SLC39A1 antibody

Western blot analysis of ZIP1 in mouse kidney tissue lysate with ZIP1 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-SLC39A1 Polyclonal Antibody – Cat# MBS150157

Immunohistochemistry (IHC) of anti-SLC39A1 antibody

Immunohistochemistry of ZIP1 in human kidney tissue with ZIP1 antibody at 2.5 μg/mL.
Rabbit Anti-SLC39A1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150157

Immunofluorescence (IF) of anti-SLC39A1 antibody

Immunofluorescence of ZIP1 in human kidney tissue with ZIP1 antibody at 20 μg/mL.
Rabbit Anti-SLC39A1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150157

Other Notes

Small volumes of anti-SLC39A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC39A1 purchase

MBS150157 is an antibody targeting SLC39A1. Also known as ZIP1 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC39A1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc transporter ZIP1 isoform a
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 1
NCBI Official Symbol
SLC39A1
NCBI Official Synonym Symbols
ZIP1; ZIRTL
UniProt Protein Name
Zinc transporter ZIP1
UniProt Synonym Protein Names
Solute carrier family 39 member 1; Zinc-iron-regulated transporter-like; Zrt- and Irt-like protein 1; ZIP-1; hZIP1
Protein Family
UniProt Gene Name
SLC39A1
UniProt Synonym Gene Names
IRT1; ZIP1; ZIRTL; ZIP-1; hZIP1
UniProt Entry Name
S39A1_HUMAN
NCBI Protein Information
zinc transporter ZIP1; zrt- and Irt-like protein 1; solute carrier family 39 (zinc transporter), member 3

NCBI Summary for SLC39A1

This gene encodes a member of the zinc-iron permease family. The encoded protein is localized to the cell membrane and acts as a zinc uptake transporter. This gene has been linked to prostate cancer, breast cancer, and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Show more

UniProt Comments for SLC39A1

SLC39A1: Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells. Belongs to the ZIP transporter (TC 2.A.5) family.

Protein type: Transporter; Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: endoplasmic reticulum membrane; membrane; integral to membrane; plasma membrane

Molecular Function: inorganic cation transmembrane transporter activity; zinc ion transmembrane transporter activity; receptor binding

Biological Process: transmembrane transport; cation transport
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000